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Investigating treatment response of patients with confirmed drug-resistant tuberculosis in an hiv-1-endemic population in western Kenya
(BMJ, 2019)
In 2015, 10.4 million people worldwide had tuberculosis (TB) and 1.4 million deaths occurred, 400 000 of whom were HIV-positive. Sub-Saharan Africa accounted for 81% of these cases. In western Kenya, current data on the ...
16S rRNA gene profiling of bacterial communities mediating production of tsetse attractive phenols in mammalian urine
(AOSIS Publishing, 2019)
Several types of odours are involved in the location of host animals by tsetse (Diptera: Glossinidae), a vector of animal African trypanosomiasis. Host animals' ageing urine has been shown to be the source of a phenolic ...
Sensitive detection of EBV microRNAs across cancer spectrum reveals association with decreased survival in adult acute myelocytic leukemia
(Scientific Report, 2019)
Epstein Barr virus (EBV) is the etiologic agent involved in numerous human cancers. After infecting
the host, EBV establishes a latent infection, with low levels of messenger RNA (mRNA) and protein
expression, evolved ...
CHAPTER EIGHTEEN A BIORATIONALE FOR CONTROL OF BIOMPHALARIA PFEIFFERI HOST SNAILS, LARVAE OF ANOPHELES GAMBIAE AND SCHISTOSOMA MANSONI
(Cambridge Scholars Publishing, 2019-11-14)
Mosquitoes transmit deadly diseases in tropical countries. Despite tremendous efforts towards disease control, the burden is still huge in endemic areas. In 2015, the region was home to 89% of malaria cases and 91% of ...
Influence of blood meal and age of mosquitoes on susceptibility to pyrethroids in Anopheles gambiae from Western Kenya
(Springer nature, 2019)
Physiological characteristics (age and blood feeding status) of malaria vectors can influence their susceptibility to the current vector control tools that target their feeding and resting behaviour. To ensure the ...
Susceptibility of Anopheles gambiae complex mosquitoes to microbial larvicides in diverse ecological settings in western Kenya. Med Vet Entomol
(Wiley, 2019)
The microbial larvicidesBacillus thuringiensisvar.israelensis(Bti) andBacillus sphaericus(Bs) (Bacillales: Bacillaceae) are well known for their efficacy andsafety in mosquito control. In order to assess their potential ...
The diagnostic accuracy of Th1 (IFN-γ, TNF-α, and IL-2) and Th2 (IL-4, IL-6 and IL-10) cytokines response in AFB microscopy smear negative PTB- HIV co-infected patients
(Springer, 2019)
Acid Fast Bacilli (AFB) microscopy smear remains the most widely used laboratory diagnostic technique
for Pulmonary Tuberculosis (PTB) in low-and-middle income countries. Although it is highly specifc,
the sensitivity ...
Molecular basis of reduced LAIR1 expression in childhood severe malarial anaemia: Implications for leukocyte inhibitory signalling
(science direct, 2019)
Leukocyte-associated immunoglobulin like receptor-1 (LAIR1) is a transmembrane inhibitory receptor that influences susceptibility to a myriad of inflammatory diseases. Our recent investigations of severe malarial anaemia ...
Spatial epidemiology of tuberculosis in the high-burden counties of Kisumu and Siaya, Western Kenya, 2012–2015
(ingenta connect, 2019)
Effective management of tuberculosis (TB) and reduction of TB incidence relies on knowledge of where, when and to what degree the disease is present.
Post-Natal Care –Health Seeking Behavior Among Women of Reproductive Age in Homa Bay Town
(British Journal of Medical and Health Research, 2019)
Postnatal care (PNC) is vital for the life of both mother and child as it reduces both marternal
and infant morbidities and mortalities. However, in Kenya, PNC utilization is low (48%) but
the cause is not known. ...