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Synergistic blending of high-valued heterocycles inhibits growth of Plasmodium falciparum in culture and P. berghei infection in mouse model
(Scientific Reports, 2017)
A series of phthalimide analogues, novelized with high-valued bioactive scaffolds was synthesized by means of click-chemistry under non-conventional microwave heating and evaluated as noteworthy growth inhibitors of ...
Assessment of palliative care services in western Kenya
(AME, 2017)
Background: The need for palliative care services is rapidly increasing due to the rising number of patients with non-communicable diseases. The objective of this study was to assess the current availability and barriers ...
Indoor and outdoor malaria vector surveillance in western Kenya: implications for better understanding of residual transmission
(Springer, 2017)
The widespread use of indoor-based malaria vector control interventions has been shown to alter the behaviour of vectors in Africa. There is an increasing concern that such changes could sustain residual transmission. This ...
Acceptable food products processed from underutilized crop
(Research Gate, 2017)
Underutilized crops are rich in micronutrients but are only cultivated at subsistence level (1). Food processing
technologies, particularly at household level, are challenging and often not applicable to traditional crops ...
Comparison of home fortification with two iron formulations among Kenyan children: Rationale and design of a placebo-controlled non-inferiority trial
(Elsevier, 2017-09-01)
Introduction
Home fortification powders containing iron and other micronutrients have been recommended by World Health Organisation to prevent iron deficiency anaemia in areas of high prevalence. There is evidence, however, ...
Diagnostic utility of zinc protoporphyrin to detect iron deficiency in Kenyan preschool children: a community-based survey
(BioMed Central, 2017-12-01)
Background
Zinc protoporphyrin (ZPP) has been used to screen and manage iron deficiency in individual children, but it has also been recommended to assess population iron status. The diagnostic utility of ZPP used in ...
Integrative microRNA and mRNA deep-sequencing expression profiling in endemic Burkitt lymphoma
(Springer, 2017)
Burkitt lymphoma (BL) is characterized by overexpression of the c-myc oncogene, which in the vast majority of cases is a consequence of an IGH/MYC translocation. While myc is the seminal event, BL is a complex amalgam of ...
Paradigm shift: efficient and cost effective real-time nutritional assessment technique
(AFRICAN SCHOLARLY SCIENCE COMMUNICATIONS TRUST (ASSCAT), 2017)
For several decades, nutritional anthropometry has been used in the assessment of
nutritional status and growth monitoring for individuals and at population level.
Techniques, equipment and standardization procedures ...
Daily home fortification with iron as ferrous fumarate versus NaFeEDTA: a randomised, placebo-controlled, non-inferiority trial in Kenyan children
(BioMed Central, 2017-12-01)
Background
We aimed to show the non-inferiority of home fortification with a daily dose of 3 mg iron in the form of iron as ferric sodium ethylenediaminetetraacetate (NaFeEDTA) compared with 12.5 mg iron as encapsulated ...
developing and implementing a Pediatric emergency Care Curriculum for Providers at district level Hospitals in sub-saharan africa: a Case study in Kenya
(Frontiers, 2017-12-11)
Introduction: Emergency medicine is a relatively new field in sub-Saharan Africa and dedicated training in pediatric emergency care is limited. While guidelines from the African Federation of Emergency Medicine (AFEM) ...