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Functional Haplotypes of Fc gamma (Fcγ) receptor (FcγRIIA and FcγRIIIB) predict risk to repeated episodes of severe malarial anemia and mortality in Kenyan children
(Springer-Verlag, 2012-02-01)
Development of protective immunity against Plasmodium falciparum is partially
mediated through binding of malaria-specific IgG to Fc gamma (γ) receptors. Variations in
human FcγRIIA-H/R-131 and FcγRIIIB-NA1/NA2 affect ...
Provider knowledge of treatment policy and dosing regimen with artemether-lumefantrine and quinine in malaria-endemic areas of western Kenya
(BioMed Central, 2012-12-29)
Due to widespread anti-malarial drug resistance in many countries, Kenya
included, artemisinin-based Combination Therapy (ACT) has been adopted as the most
effective treatment option against malaria. Artemether-lumefantrine ...
Polymorphisms in the Fc Gamma Receptor IIIA and Toll-Like Receptor 9 Are Associated with Protection against Severe Malarial Anemia and Changes in Circulating...
(Journals. ASm. org, 2012-10-08)
An understanding of the immunogenetic basis of naturally acquired immunity to Plasmodium
falciparum infection would aid in the designing of a rationally based malaria vaccine.
Variants within the Fc gamma receptors ...
Communicating African spirituality through ecology: Challenges and prospects for the 21st century
(2012-06-19)
This review was set in the context of African spirituality and ecology. Specifically,
the review addressed issues of African spirituality and the environment from a Kenyan
context. Through analyses on existing literature, ...
Functional Haplotypes of Fc Gamma (Fcy) Receptor (FcyRIIA and FcyRIIB) Predict Risk to Repeated Episodes of Severe Malarial Anaemia and Mortality in Kenyan...
(SN Konah, 2012)
Development of protective immunity against Plasmodium falciparum is partially mediated
through binding of malaria-specific IgG to Fc gamma (γ) receptors. Variations in human
FcγRIIA-H/R-131 and FcγRIIIB-NA1/NA2 affect ...
Functional promoter haplotypes of interleukin-18 condition susceptibility to severe malarial anemia and childhood mortality.
(PubMed, 2012)
Severe malarial anemia (SMA) is a leading cause of morbidity and mortality in children
residing in regions where plasmodium falciparum transmission is holoendemic. Although
largely unexplored in children with SMA, ...
Haplotypes of IL12B promoter polymorphisms condition susceptibility to severe malaria and functional changes in cytokine levels in Thai adults
(Immunogenetics, 2012)
Polymorphic variability in immune response genes, such as IL12B, encoding the IL-12p40
subunit is associated with susceptibility to severe malaria in African populations. Since the
role of genetic variation in conditioning ...
Polymorphisms in Fc gamma receptor (FcγRIIIA-176 F/V) and Toll-like receptor (TLR9 [-1237 T/C]) are associated with protection against severe malarial anemia an...
(American Society for Microbiology, 2012-10-08)
Understanding the immunogenetic basis of naturally acquired immunity to
Plasmodium falciparum infection would aid in designing a rationally-based malaria vaccine.
Variants within the Fc gamma receptors (FcγRs) mediate ...
Upregulation of Peripheral Blood Levels of Immune-Regulatory Interleukin-10 Cytokine in Human Immunodeficiency Virus-infected Compared to Non-infected Pregn...
(2012)
Alterations in the cytokine status have been suggested to be at least partly
responsible for the immune tolerance during pregnancy. Indeed, interleukin-10 (IL-10)
cytokine is known to control inflammationinduced ...
Social and Demographic Characteristics of HIV-Positive Mother-Infant Pair and Their Association with Mother-To-Child Transmission of HIV in Vihiga, Kakamega, Bu...
(2012)
The World Health Organization report indicates that in 2013~ 35
million people worldwide lived with HIV and AIDS. Of these, 3.2 million were children age<
15 years. The proportion of women living with HIV has remained ...