Browsing School of Public health & Community Development by Issue Date
Now showing items 41-60 of 402
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Bacteremia in Kenyan children presenting with malaria
(American Society for Microbiology, 2011-02-01)Since the etiologies and clinical outcomes of bacteremia in children with Plasmodium falciparum infections, particularly in areas of holoendemic malaria transmission, are largely unexplored, blood cultures and comprehensive ... -
Turning point
(Nature Research, 2011-02-01)Collins Ouma became a molecular biologist to help thwart malaria's high mortality rate in his native Kenya. Last November, he won the Royal Society Pfizer award for his work on identifying genes that may confer protection ... -
Knowledge and behaviour as determinants of anti-malarial drug use in a peri-urban population from malaria holoendemic region of western Kenya
(BioMed Central, 2011-04-20)The appropriate use of anti-malarial drugs determines therapeutic efficacy and the emergence and spread of drug-resistant malaria. Strategies for improving drug compliance require accurate information about current ... -
Using Food Grade Lye “omushelekha” in the Formulation of Health Products from Commonly Consumed African Indigenous Vegetables and Vegetable Combinations
(Functional Foods in Health and Disease, 2011-05-24): Lye, sodium hydroxide and potassium hydroxide has been used over the years in food preparation including the preparation of vegetables and dried meat products, washing or chemical peeling of fruits and vegetables, cocoa ... -
Polymorphic variability in the 3'untranslated region (UTR) of IL12B is associated with susceptibility to severe anaemia in Kenyan children with acute Plasmodium falc...
(BioMed Central, 2011-08-06)Plasmodium falciparum malaria remains a leading cause of morbidity and mortality among African children. Innate immunity provides the first line of defence against P. falciparum infections, particularly in young children ... -
Natural monocytic acquisition of haemozoin and rantes polymorphisms: association with malarial disease outcomes and functional changes in children from Wester...
(2011-08-15)Plasmodium falciparum is an important cause of morbidity and mortality in children residing in holoendemic transmission areas largely from severe malarial anaemia (SMA). Although overproduction of inflammatory-derived ... -
Relationship of the availability of micronutrient powder with iron status and hemoglobin among women and children in the Kakuma Refugee Camp, Kenya
(SAGE Publications, 2011-09)Background Micronutrient powder is a potential strategy to improve iron status and reduce anemia in refugee populations. Objective To evaluate the effect of the availability of home fortification with a micronutrient ... -
Food preparation and processing methods on nutrient retention and accessibility in selected indigenous vegetables from East Africa
(Research gate, 2012)In Africa, indigenous vegetables are a common food source and rich source of micronutrients such as carotenoids, vitamin C, calcium and iron. However, food preparation and processing operations affect contents and ... -
A holistic approach to natural resource management: A case of Lake Victoria Basin
(CRC Press, 2012)Lake Victoria (LV), with a surface area of about 68,870 km2, is Africa’s largest and the world’s second largest freshwater lake. It lies at an altitude of 1134 m above sea level and relatively shallow with a maximum depth ... -
Functional Haplotypes of Fc Gamma (Fcy) Receptor (FcyRIIA and FcyRIIB) Predict Risk to Repeated Episodes of Severe Malarial Anaemia and Mortality in Kenyan...
(SN Konah, 2012)Development of protective immunity against Plasmodium falciparum is partially mediated through binding of malaria-specific IgG to Fc gamma (γ) receptors. Variations in human FcγRIIA-H/R-131 and FcγRIIIB-NA1/NA2 affect ... -
Functional promoter haplotypes of interleukin-18 condition susceptibility to severe malarial anemia and childhood mortality.
(PubMed, 2012)Severe malarial anemia (SMA) is a leading cause of morbidity and mortality in children residing in regions where plasmodium falciparum transmission is holoendemic. Although largely unexplored in children with SMA, ... -
Polymorphic Variability in the Interleukin (IL)-1Beta Promoter Conditions Susceptibility to Severe Malarial Anemia and Functional Changes in IL-1Beta Production
(PubMed, 2012)Interleukin (IL)-1beta is a cytokine released as part of the innate immune response to Plasmodium falciparum. Because the role played by IL-1beta polymorphic variability in conditioning the immunopathogenesis of severe ... -
Haplotypes of IL12B promoter polymorphisms condition susceptibility to severe malaria and functional changes in cytokine levels in Thai adults
(Immunogenetics, 2012)Polymorphic variability in immune response genes, such as IL12B, encoding the IL-12p40 subunit is associated with susceptibility to severe malaria in African populations. Since the role of genetic variation in conditioning ... -
MIF (macrophage migration inhibitory factor) promoter polymorphisms and susceptibility to severe malarial anemia
(Journal of Infectious Diseases, 2012)Severe malarial anemia (SMA) resulting from Plasmodium falciparum infection is one of the leading causes of childhood mortality in sub-Saharan Africa. The innate immune mediator macrophage migration inhibitory factor ... -
Upregulation of Peripheral Blood Levels of Immune-Regulatory Interleukin-10 Cytokine in Human Immunodeficiency Virus-infected Compared to Non-infected Pregn...
(2012)Alterations in the cytokine status have been suggested to be at least partly responsible for the immune tolerance during pregnancy. Indeed, interleukin-10 (IL-10) cytokine is known to control inflammationinduced ... -
Knowledge, attitude and practice towards zoonoses among public health workers in Nyanza province, Kenya
(J Epidemiol Public Health Rev, 2012)We sought to determine the knowledge and attitude of public health workers (PHWs) with respect to emerging and re-emerging zoonotic diseases and the practice of one health approach in the surveillance of zoonoses in the ... -
Social and Demographic Characteristics of HIV-Positive Mother-Infant Pair and Their Association with Mother-To-Child Transmission of HIV in Vihiga, Kakamega, Bu...
(2012)The World Health Organization report indicates that in 2013~ 35 million people worldwide lived with HIV and AIDS. Of these, 3.2 million were children age< 15 years. The proportion of women living with HIV has remained ... -
Sputum Smear Conversion Time of HIV Infected and Uninfected Patients with Rifampicin and Isoniazid Mycobacterium tuberculosis gene Mutations in Western Kenya
(2012)Mono-resistant and multi-drug resistant tuberculosis (MDR-TB) has been enhanced by delays in the identification of resistant strains. However, resistance gene patterns and the extent of monoresistant TB and MDR-TB in ... -
Dose-Effects of Bednets Impregnated with a Natural Pyrethrins Formulation: Persistence, Feeding Inhibition, and Wash Resistance against Anopheles gambiae ss
(2012)This study evaluated dose-response, persistence, irritancy and wash resistance of mosquito nets treated with a synergized natural pyrethrins-formulation against Anopheles gambiae ss Methods. Multi-filament polyester ...