Browsing School of Public health & Community Development by Title
Now showing items 220-239 of 384
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Low Levels of Human Antibodies to Gametocyte-Infected Erythrocytes Contrasts the PfEMP1-Dominant Response to Asexual Stages in P. falciparum Malaria
(Frontier in Immunology, 2018)Vaccines that target Plasmodium falciparum gametocytes have the potential to reduce malaria transmission and are thus attractive targets for malaria control. However, very little is known about human immune responses to ... -
Low reliability of home-based diagnosis of malaria in a rural community in western Kenya
(2011)Home-based management of malaria is promoted as a major strategy for improving prompt delivery of effective malaria treatment in Africa. This study aimed to determine the proportion of children who tested positive for ... -
Low sensitivity of the careHPV™ Assay for detection of Oncogenic Human Papillomavirus in cervical samples from HIV-infected and HIV-uninfected Kenyan women
(HSPC, 2020)Human papillomavirus (HPV) infection causes cervical cancer (CC), a common malignancy among Kenyan women. New CC screening methods rely on oncogenic HPV (“highrisk”, or HR-HPV) detection, but most have not been evaluated ... -
A machine learning approach to integrating genetic and ecological data in tsetse flies (Glossina pallidipes) for spatially explicit vector control planning. Evolutionary Applications.
(PMC US National Library of Medicine National Institutes of Health, 2021)Vector control is an effective strategy for reducing vector‐borne disease transmission, but requires knowledge of vector habitat use and dispersal patterns. Our goal was to improve this knowledge for the tsetse species ... -
Malaria in Kakuma refugee camp, Turkana, Kenya: facilitation of Anopheles arabiensis vector populations by installed water distribution and catchment systems
(BioMed Central, 2011)Background: Malaria is a major health concern for displaced persons occupying refugee camps in sub-Saharan Africa, yet there is little information on the incidence of infection and nature of transmission in these ... -
Mapping geographic clusters of new HIV diagnoses to inform granular-level interventions for HIV epidemic control in western Kenya
(BMC Public Health, 2021)As countries make progress towards HIV epidemic control, there is increasing need to identify finer geographic areas to target HIV interventions. We mapped geographic clusters of new HIV diagnoses, and described factors ... -
Maternal Factors Influencing Under-five Mortality in Karemo Sub-county in Siaya County, Kenya
(Research Square, 2023-03)Background Despite the substantial reduction of under-five mortality (U5M) across the world, about 15,000 under-fives (U5s) die daily. Majority occurs in developing countries with Sub-Saharan African countries like Kenya ... -
Measuring health system resilience in a highly fragile nation during protracted conflict: South Sudan 2011–15
(Health Policy and Planning, 2020)Health systems resilience (HSR) is defined as the ability of a health system to continue providing normal services in response to a crisis, making it a critical concept for analysis of health systems in fragile and ... -
Measuring Men’s Gender Norm Beliefs Related to Contraception: Development of the Masculine Norms and Family Planning Acceptance Scale
(Springer, 2021)Male partner resistance is identified as a key factor that influences women’s contraceptive use. Examination of the masculine norms that shape men’s resistance to contraception—and how to intervene on these norms—is needed. ... -
Mechanisms and targets of Fcγ-receptor mediated immunity to malaria sporozoites
(Nature Communications, 2021)A highly protective vaccine will greatly facilitate achieving and sustaining malaria elimination. Understanding mechanisms of antibody-mediated immunity is crucial for developing vaccines with high efficacy. Here, we ... -
Medicinal Properties and Active Constituents of Dracocephalum kotschyi and Its Significance in Iran: A Systematic Review
(Hindawi, 2019)Objectives. Dracocephalum has over 60 species and is found mainly in the temperate regions of Asia and Europe. One of these species, i.e., Dracocephalum kotschyi Boiss, is known to have a number of medicinal properties and ... -
Metabollic syndrome components as a risk factor to the health status of university students in Kenya
(IJCIRAS, 2019)An efficient healthcare system targets the maintenance or improving the health position for citizens that can be achieved through disease and illness prevention based on curative and preventive care. Kenya currently ... -
Metagenomic analysis of the microbiota in the highly compartmented hindguts of six wood-or soil-feeding higher termites
(BioMed Central, 2015-12-01)Termites are important contributors to carbon and nitrogen cycling in tropical ecosystems. Higher termites digest lignocellulose in various stages of humification with the help of an entirely prokaryotic microbiota housed ... -
“Methanoplasmatales,” Thermoplasmatales-related archaea in termite guts and other environments, are the seventh order of methanogens
(American Society for Microbiology, 2012-12-01)The Euryarchaeota comprise both methanogenic and nonmethanogenic orders and many lineages of uncultivated archaea with unknown properties. One of these deep-branching lineages, distantly related to the Thermoplasmatales, ... -
Microgeographic Epidemiology of Malaria Parasites in an Irrigated Area of Western Kenya by Deep Amplicon Sequencing
(IDSA, 2021)To improve food security, investments in irrigated agriculture are anticipated to increase throughout Africa. However, the extent to which environmental changes from water resource development will impact malaria epidemiology ... -
MIF (macrophage migration inhibitory factor) promoter polymorphisms and susceptibility to severe malarial anemia
(Journal of Infectious Diseases, 2012)Severe malarial anemia (SMA) resulting from Plasmodium falciparum infection is one of the leading causes of childhood mortality in sub-Saharan Africa. The innate immune mediator macrophage migration inhibitory factor ... -
A Model on the Impact of Treating Typhoid with Anti-malarial: Dynamics of Malaria Concurrent and Co-infection with Typhoid
(2015)International Journal of Mathematical Analysis Vol. 9, 2015, no. 11, 541 - 551 HIKARI Ltd, www.m-hikari.com http://dx.doi.org/10.12988/ijma.2015.412403 … A Model on the Impact of Treating Typhoid with … Department ... -
Modelling the Impact of Misdiagnosis and Treatment on the Dynamics of Malaria Concurrent and Co-infection with Pneumonia
(2013)Incidences of misdiagnosis of diseases with similar symptoms as malaria has increased lately due to the increasing levels of endemicity of these diseases and their co- infection with malaria. In this paper a mathematical ... -
Molecular basis of reduced LAIR1 expression in childhood severe malarial anaemia: Implications for leukocyte inhibitory signalling
(science direct, 2019)Leukocyte-associated immunoglobulin like receptor-1 (LAIR1) is a transmembrane inhibitory receptor that influences susceptibility to a myriad of inflammatory diseases. Our recent investigations of severe malarial anaemia ... -
Molecular epidemiology of Brucella species in mixed livestock-human ecosystems in Kenya
(Nature Publishing Group, 2021)Brucellosis, caused by several species of the genus Brucella, is a zoonotic disease that affects humans and animal species worldwide. Information on the Brucella species circulating in different hosts in Kenya is largely ...
