Browsing Cell and Molecular Biology by Issue Date
Now showing items 1-16 of 16
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Binding of opsonized immune complexes to Erythrocyte crlicd35 inhibits TNF-a production by restricting immune complex uptake by macro phages
(Maseno university, 2008)Previous studies have shown that children suffering from severe malaria have elevated concentrations of TNF-a, increased levels of circulating immune complexes (ICs) and decreased levels of complement regulatory proteins ... -
The functional associations between il-4 -589t/c and Il-6 -636g/c promoter polymorphisms and paediatric Severe malarial anaemia in a holoendemic area of Western Kenya
(Maseno university, 2009)Plasmodium falciparum, the most virulent and lethal human malaria parasite, IS responsible for most malaria-related morbidity and mortality in sub-Saharan Africa. It manifests mainly as severe malarial anaemia (SMA) in ... -
Phenotypic and genotypic characterization of salmonella Isolated from Nile tilapia (Oreochromis ni/otics, L.) Along lake Victoria beaches in western Kenya
(Maseno university, 2009)Enteritis induced by nontyphoidal Salmonella represents major economic and social problems. Chemotherapeutic selection may have additional consequences for virulence evolution through acquisition of linked virulence ... -
Apoptotic machinery in plasmodium falciparum Growing in a continuous culture
(Maseno university, 2009)Apoptosis and indeed metacaspase have not been sufficiently evaluated to show their role in Plasmodium Jalciparum. To study apoptosis, synchronized P. Jalciparum cultures were initiated at a parasitemia of 0.5 % at 5 % ... -
Pathogenesis of Schistosomiasis and HIV Co-infecfion: Polymorpmsms in Il-23 Receptor in Schistosomiasis Patients undergoing Highly Active Antiretroviral Therapy (HAART)
(Maseno University, 2013)IllY and schistosomiasis co-infection is common around Lake Victoria region, raising the possibility of schistosomiasis-related immune reconstitution inflammatory syndrome (IRIS) in patients undergoing mv medication. Some ... -
Determination of Antimicrobial Resistance of Escherichia Coli Isolated From Rastrineobola Argentea and Water Samples From Lake Victoria - Kenya
(Maseno University, 2014)Many strains of Escherichia coli can be pathogenic leading to diarrheal diseases. The occurrence of antimicrobial resistant bacteria is increasing in aquatic environments infecting fish which are later consumed by humans ... -
Additive stabilization of plasmodium proteins present in dried infected blood specimens
(Maseno University, 2016)Malaria rapid diagnostic tests (RDTs) are a great achievement to the implementation of parasite based diagnosis before treatment. They use a nitrocellulose strip coated with antibodies that target the Plasmodium antigens; ... -
Susceptibility patterns and tolerance mechanisms of Staphylococcus Epidermidis biofilms to Physico-chemical stress exposure
(Maseno University, 2018)Bacterial biofilms remain a major public health burden. Staphylococcus epidermidis biofilm is the predominant cause of biofilm-associated infections. Kisumu county has a high circulation of antibiotic resistance genes, ... -
Genome-wide comparative study of epstein-barr virus genomic recombination in endemic burkitt lymphoma and healthy children from jootrh, western Kenya
(Maseno university, 2022)Endemic Burkitt lymphoma (eBL), the most prevalent pediatric cancer in Western Kenya, is augmented by the interplay between Epstein-Barr Virus (EBV) and holoendemic malaria infection. Despite the relevance of genomic ... -
HEMATOLOGICAL AND BIOCHEMICAL PARAMETERS AS ALTERNATIVE MARKERS OF STOCKING DENSITY- INDUCED STRESS IN CULTURED NILE TILAPIA, (Oreochromis niloticus Linnaeus, 1758) UNDER CULTURE CONDITIONS.
(Maseno University, 2022)Fish and fisheries play a significant role in meeting nutritional food security, more so of the poor communities in the low and middle income countries (LMIC).Oreochromis niloticusisone the most valuable warm water fishes ... -
Relationship between the concentration of microcystin in serum and primary liver cancer in patients attending JOOTRH, Kisumu, Kenya
(Maseno University, 2022)Microcystins (MCs) are toxins released by unicellular micro-organism known as cyanobacteria. These unicellular micro-organisms flourish in aquatic habitats with warm temperatures and nutrients rich water bodies. Microcystins ... -
Evaluation of anti-leishmanial activities of Olea europaea, Kigelia africana, Terminalia mollis, Croton macrostachyus, and Bridella micrantha extracts
(Maseno University, 2023)Leishmaniasis pose a significant medical concern worldwide which if left untreated, can be fatal. Although expensive and toxic, pentavalent antimonial drugs are the first-line treatment for leishmaniasis raising the need ... -
Association between hiv-1 subtypes and drug resistance to first line therapy among individuals with advanced disease in Homa bay county, Kenya
(Maseno University, 2023)Human Immunodeficiency Virus-1 remains a public health threat globally, and although antiretroviral therapy has greatly improved the lives of people living with HIV, challenges persist due to high HIV genetic diversity and ... -
Sero-prevalence of Brucellosis and associated risk factors to Brucella pathogen in Tiaty, Baringo County, Kenya
(Maseno University, 2023)Brucellosis is a global zoonotic disease caused by Brucella pathogen, which affects man and animals. The disease has been reported across the world including Kenya. Information regarding the sero-prevalence and risk factors ... -
Molecular determination of Plasmodium falciparum parasites with histidine-rich protein 2/3 gene deletions in a holoendemic area, Siaya county, western Kenya
(Maseno University, 2023)Malaria remains endemic in western Kenya despite the various control interventions. Accurate diagnosis is key to the treatment and control of malaria. As such, the World Health Organization (WHO) recommends parasite-based ... -
Prevalence and antibiotic susceptibility patterns of cotrimoxazole resistant bacterial uropathogens from Hiv patients attending Maseno mission hospital, western kenya
(Maseno University, 2023)Urinary tract infections (UTI) are inflammatory disorders within the urinary system due to presence of pathogenic microorganisms. Taking advantage of lowered immunity in Human Immuno-deficiency Virus (HIV) patients, bacterial ...