Correlation Between Malaria-Specific Antibody Profiles and Responses to Artemisinin Combination Therapy for Treatment of Uncomplicated Malaria in Western Kenya
Geoffrey Odhiambo, Walter Elke Bergmann-Leitner, Moureen Maraka, Christine NL Wanjala, Elizabeth Duncan, John Waitumbi, Ben Andagalu, Walter GZO Jura, Sheetij Dutta, Evelina Angov, Bernhards R Ogutu, Edwin Kamau, Daniel Ochiel
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The impact of preexisting immunity on the efficacy of artemisinin combination therapy must be examined to monitor resistance, and for implementation of new treatment strategies
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Malaria prevalence defined by microscopy, antigen detection, DNA amplification and total nucleic acid amplification in a malaria-endemic region during the peak malaria transmission season Waitumbi, JN; Gerlach, J; Afonina, I; Anyona, SB; Koros, JN; Siangla, J; Ankoudinova, I; Singhal, M; Watts, K; Polhemus, ME; Vermeulen, NM; Mahoney, W; Steele, M; Domingo, GJ (Pub Med Central, 2011-07)OBJECTIVES: To determine the malaria prevalence by microscopy, antigen detection and nucleic acid detection in a defined subpopulation in a Plasmodium falciparum-endemic region during the peak transmission season. ME ...
Estimating Annual Fluctuations in Malaria Transmission Intensity and in the Use of Malaria Control Interventions in Five Sub-Saharan African Countries RTS, S Epidemiology EPI-MAL-005 Study Group, Elisha Adeniji, Kwaku Poku Asante, Owusu Boahen, Guillaume Compaoré, Boubacar Coulibaly, Seyram Kaali, Youssouf Kabore, Mathieu Lamy, John Lusingu, Anangisye Malabeja, Petra Mens, Mattéa Orsini, Lucas Otieno, Walter Otieno, Seth Owusu-Agyei, Janet Oyieko, Jean-Yves Pirçon, Nicolas Praet, François Roman, Ali Sie, Valentine Sing’oei, Sodiomon B Sirima, Khadime Sylla, Roger Tine, Alfred B Tiono, Mathilda Tivura, Effua Usuf, Stéphanie Wéry (The American Society of Tropical Medicine and Hygiene, 2020)RTS,S/AS01E malaria vaccine safety, effectiveness, and impact will be assessed in pre- and post-vaccine introduction studies, comparing the occurrence of malaria cases and adverse events in vaccinated versus unvaccinate ...
Effect of malaria rapid diagnostic tests on the management of uncomplicated malaria with artemether-lumefantrine in Kenya: a cluster randomized trial Jacek Skarbinski, Peter O Ouma, Louise M Causer, Simon K Kariuki, John W Barnwell, Jane A Alaii, Alexandre Macedo de Oliveira, Dejan Zurovac, Bruce A Larson, Robert W Snow, Alexander K Rowe, Kayla F Laserson, Willis S Akhwale, Laurence Slutsker, Mary J Hamel (The American Society of Tropical Medicine and Hygiene, 2009)Shortly after Kenya introduced artemether-lumefantrine (AL) for first-line treatment of uncomplicated malaria, we conducted a pre-post cluster randomized controlled trial to assess the effect of providing malaria rapid ...