Department of Obstetrics & Gynecology: Recent submissions
Now showing items 1-20 of 23
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Phase I study on the pharmacokinetics of intravaginal, self-administered artesunate vaginal pessaries among women in Kenya
(Cold Spring Harbor Laboratory Press, 2024-07-08)Cervical cancer remains a significant global health issue, especially in low- and middle-income countries (LMICs), where access to prevention and treatment is limited and women are at a higher risk of cervical cancer. ... -
“There is nothing that can prevent me from supporting her:” men’s perspectives on their involvement and support of women’s use of topical therapy for cervical precancer treatment in Kenya
(Frontiers, 2024-03-12)Cervical cancer disproportionately impacts women in low- and middle-income countries (LMICs). The World Health Organization’s (WHO) 90/70/90 strategy aims to eliminate cervical cancer by 2030 by increasing HPV vaccination ... -
Perceived acceptability of self-administered topical therapy for cervical precancer treatment among women undergoing cervical cancer screening in Kenya
(Cold Spring Harbor Laboratory Press, 2024-03-05)Innovative strategies are urgently needed to meet the World Health Organizations 2030 target of treating 90% of women with precancerous cervical lesions, especially in countries most affected by cervical cancer. We assessed ... -
Efficacy of thermal ablation for treatment of biopsy‐confirmed high‐grade cervical precancer among women living with HIV in Kenya
(John Wiley & Sons, Inc., 2023-09-15)The World Health Organization recommends thermal ablation (TA) as an alternative to cryotherapy within “screen-and-treat” cervical cancer programs in low- and middle-income countries (LMICs), including among women living ... -
Association of Plasma Aflatoxin With Persistent Detection of Oncogenic Human Papillomaviruses in Cervical Samples From Kenyan Women Enrolled in a Longitudinal Study
(Research Square, 2023)Cervical cancer is common among Kenyan women and is caused by oncogenic human papillomaviruses (HR-HPV). Identification of factors that increase HR-HPV persistence is critically important. Kenyan women exposed to aflatoxin ... -
Effects of Training Small-Scale Farmers on Food Security in Moiben Sub County in Uasin Gishu County
(EANSO, 2022)Food security revolves around equality in the availability, access, and intake of nutritious food. The main purpose of this research is to determine the effectiveness of the adoption of agricultural technologies by small-scale ... -
Negotiating Access to Maternal Health Services During COVID-19 Pandemic in Kilifi County, Kenya: Rapid Qualitative Study
(Springer, Singapore, 2022)Globally, women do a lot of unpaid work even before the onset of the COVID-19 pandemic. COVID-19 has delivered a blow to existing gender systems that could recalibrate gender roles, positively affecting population health. ... -
Food Security Status During The Covid-19 Pandemic Among Vulnerable Groups In Keiyo South, Elgeyo Marakwet County, Kenya
(International Journal of Scientific and Research Publications, 2021)Health guidelines to manage the COVID-19 pandemic could have led to unintended changes in states and processes that affect food systems, food security, and nutrition. The study conducted in Elgeyo Marakwet County, Kenya ... -
Healthcare provider and pregnant women’s perspectives on the implementation of intermittent screening and treatment with dihydroartemisinin–piperaquine for malaria in pregnancy in western Kenya: a qualitative study
(BioMed Central, 2021)In malaria endemic regions in Kenya, pregnant women are ofered long-lasting insecticidal nets and intermittent preventive treatment (IPTp) with sulfadoxine–pyrimethamine (SP) at antenatal care (ANC) to prevent the adverse ... -
Validation of Chloe SED, a Low-Cost, Reusable Syringe Extension Device for the Provision of Paracervical Analgesia [A21]
(LWW, 2022)Women in Kenya and other low- and middle-income countries often do not receive analgesia during manual vacuum aspiration (MVA). This pilot study evaluated the efficacy of a novel, ultra-low-cost syringe extension device ... -
Development and initial validation of a pictorial survey to assess for symptomatic pelvic organ prolapse and urinary incontinence in western Kenya
(Springer International Publishing, 2022)Visual tools are a valuable tool for ascertaining patient symptoms, especially in populations with low literacy rates. The objective was to develop and validate a pictorial scale for assessing symptomatic pelvic organ ... -
Burden of malaria in pregnancy among adolescent girls compared to adult women in 5 sub-Saharan African countries: A secondary individual participant data meta-analysis of 2 clinical trials
(PLOS MEDICINE, 2022)Malaria is among the top causes of death in adolescent girls (10 to 19 years) globally. Adolescent motherhood is associated with increased risk of adverse maternal and neonatal outcomes. The interaction of malaria, ... -
Efficacy of Thermal Ablation for Treatment of High-Grade Cervical Dysplasia Among HIV-Positive Women: Preliminary Results From Western Kenya
(Wolters Kluwer Health, 2022)In 2019, the World Health Organization (WHO) endorsed thermal ablation (TA) for use within “screen-and-treat” cervical cancer prevention programs in low- and middle-income countries (LMICs), including among women living ... -
Validation of Chloe SED, a Low-Cost, Reusable Syringe Extension Device for the Provision of Paracervical Analgesia [A21]
(LWW, 2022)Women in Kenya and other low- and middle-income countries often do not receive analgesia during manual vacuum aspiration (MVA). This pilot study evaluated the efficacy of a novel, ultra-low-cost syringe extension device ... -
A cross-sectional analysis of factors associated with detection of oncogenic human papillomavirus in human immunodeficiency virus-infected and uninfected Kenyan women
(BMC journal, 2019)Cervical cancer is caused by oncogenic human papillomaviruses (HPV) and is one of the most common malignancies in women living in sub-Saharan Africa. Women infected with the human immunodeficiency virus (HIV) have a higher ... -
Feasibility and Acceptability of Smartphone-Based Cervical Cancer Screening Among HIV-Positive Women in Western Kenya
(Global Oncology, 2021)Adjunct cervical cancer screening methods are under evaluation to improve the diagnostic accuracy of human papillomavirus (HPV)-based screening in low- and middle-income countries. We evaluated the feasibility and acceptability ... -
Impact of sulfadoxine-pyrimethamine resistance on effectiveness of intermittent preventive therapy for malaria in pregnancy at clearing infections and preventing low birth weight
(Oxford University Press, 2016-02-01)Owing to increasing sulfadoxine-pyrimethamine (SP) resistance in sub-Saharan Africa, monitoring the effectiveness of intermittent preventive therapy in pregnancy (IPTp) with SP is crucial -
Factors affecting antenatal care attendance: results from qualitative studies in Ghana, Kenya and Malawi
(Public Library of Science, 2013-01-15)Antenatal care (ANC) is a key strategy to improve maternal and infant health. However, survey data from subSaharan Africa indicate that women often only initiate ANC after the first trimester and do not achieve the ... -
Enhanced postoperative surveillance versus standard of care to reduce mortality among adult surgical patients in Africa (ASOS-2): a cluster-randomised controlled trial
(Elsevier, 2021)Risk of mortality following surgery in patients across Africa is twice as high as the global average. Most of these deaths occur on hospital wards after the surgery itself. We aimed to assess whether enhanced postoperat ... -
Feasibility and Acceptability of Smartphone-Based Cervical Cancer Screening Among HIV-Positive Women in Western Kenya
(Gynecologic Cancer, 2021)PURPOSE Adjunct cervical cancer screening methods are under evaluation to improve the diagnostic accuracy of human papillomavirus (HPV)-based screening in low- and middle-income countries. We evaluated the feasibility and ...
