School of Medicine: Recent submissions
Now showing items 401-420 of 553
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Toward Cervical Cancer Elimination: Evaluation of Access to Diagnostic Services After Referral to a Specialist Gynecologist Clinic at a Major Referral Hospital in Kisumu, Kenya
(American Society of Clinical Oncology, 2020-07)Women in low- and middle-income countries bear a disproportionate burden of cervical cancer incidence and mortality. WHO recommends screening with visual inspection with acetic acid (VIA), followed by treatment in a ... -
Cryptococcus Meningitis in a Cohort of HIV Positive Kenyan Patients: Outcome after Two Weeks of Therapy
(East African Medical Journal, 2013)Background: Cryptococcus meningitis is the most lethal meningitis in patients with HIV/AIDS. It is invariably fatal if not treated appropriately and promptly. In sub- Saharan Africa with the highest prevalence of HIV/AIDS, ... -
Factors underlying stigmatization of epilepsy: A comparative case study of Suba and Meru Central Districts, Kenya
(American Scientific Research Journal for Engineering, Technology, and Sciences (ASRJETS), 2014)Epilepsy is the most common neurological disorder known to mankind. It is shrouded in mystery and associated with supernatural forces resulting in social stigma, systematic discrimination and psychological morbidity to the ... -
Prevalence and Factors Associated with Depression among Patients with Epilepsy at Aga Khan University Teaching Hospital Nairobi
(2015-10-01)Objective: To determine the prevalence and factors associated with depression in patients with epilepsy at Aga Khan University Hospital; Nairobi. Design: A Cross-Sectional Survey. Setting: Neurology clinic, Aga Khan ... -
Effects Of Catha edulis’ Leaf Extract on Blood Chemistry and Kidney Tissues in Small East African Male Goats from Rift Valley Province of Kenya
(East African Medical Journal, 2014)Objectives: To determine the serum electrolytes levels in animals treated with Catha edulis leaf extract. Design: Experimental study Setting: Department of Biological Sciences at the Chepkoilel University College, ... -
Student Politics in Africa
(African Minds, 2016)The second volume of the African Higher Education Dynamics Series brings together the research of an international network of higher education scholars with interest in higher education and student politics in Africa. Most ... -
Internationalization of Higher Education, Africa
(Internationalization of Higher Education, Africa, 2018)Internationalization finds expression through travel abroad by students, faculty engaged in collaborative research and publishing, signing of memoranda of understanding between foreign institutions, when satellite campuses ... -
Cardiovascular risk factors among people living with HIV in rural Kenya: a clinic-based study
(Clinics Cardive Publishing, 2019-07-01)Objectives: To determine the prevalence of cardiovascular risk factors and their association with antiretroviral therapy (ART) among HIV-infected adults in a rural sub-county hospital in Kenya. Methods: This was a ... -
Expression profiling of Trypanosoma congolense genes during development in the tsetse fly vector Glossina morsitans morsitans
(BioMed Central, 2018-12)The tsetse transmitted parasitic flagellate Trypanosoma congolense causes animal African trypanosomosis (AAT) across sub-Saharan Africa. AAT negatively impacts agricultural, economic, nutritional and subsequently, health ... -
Reduced interferon (IFN)-α conditioned by IFNA2 (− 173) and IFNA8 (− 884) haplotypes is associated with enhanced susceptibility to severe malarial anemia and longitudinal all
(Springer-Verlag, 2012-08-01)Severe malarial anemia (SMA) is a leading cause of pediatric morbidity and mortality in holoendemic Plasmodium falciparum transmission areas. Although dysregulation in cytokine production is an important etiology of SMA, ... -
The Global Burden of Severe Falciparum Malaria: An Immunological and Genetic Perspective on Pathogenesis
(Springer, New York, NY, 2013)Plasmodium falciparum malaria is a leading global cause of morbidity and mortality of infectious disease origin. Here, we focus largely on P. falciparum malaria in sub-Saharan Africa since this geographic region bears the ... -
Interleukin (IL)-13 promoter polymorphisms (-7402 T/G and-4729G/A) condition susceptibility to pediatric severe malarial anemia but not circulating IL-13 levels
(BioMed Central, 2013-12-01)In holoendemic Plasmodium falciparum transmission areas such as western Kenya, severe malarial anemia [SMA, hemoglobin (Hb) < 6.0 g/dL, with any density parasitemia] is the most common clinical manifestation of severe ... -
Duffy Antigen/Receptor for Chemokines (DARC): Is There a Role in Prostate Cancer?.
(American Society of Hematology, 2005-11-16)Introduction: The Duffy blood group antigens function as chemokine receptors and as receptors for several species of malarial parasites. Approximately 70% of African Americans are Duffy negative as a result of a single ... -
Direct detection of bacteremia by exploiting host-pathogen interactions of lipoteichoic acid and lipopolysaccharide
(Nature Publishing Group, 2019-04-17)Bacteremia is a leading cause of death in sub-Saharan Africa where childhood mortality rates are the highest in the world. The early diagnosis of bacteremia and initiation of treatment saves lives, especially in high-disease ... -
Integrated OMICS platforms identify LAIR1 genetic variants as novel predictors of cross-sectional and longitudinal susceptibility to severe malaria and all-cause mortality in …
(Elsevier, 2019-07-01)Background: Severe malarial anaemia (SMA) is a leading cause of childhood mortality in holoendemic Plasmodium falciparum regions. Methods: To gain an improved understanding of SMA pathogenesis, whole genome and transcriptome ... -
Evaluation of the Parasight platform for malaria diagnosis
(American Society for Microbiology Journals, 2017-03-01)The World Health Organization estimates that nearly 500 million malaria tests are performed annually. While microscopy and rapid diagnostic tests (RDTs) are the main diagnostic approaches, no single method is inexpensive, ... -
A novel ED-based sexual assault centre in western Kenya: description of patients and analysis of treatment patterns
(BMJ Publishing Group Ltd and the British Association for Accident & Emergency Medicine, 2011-11-01)he aim of this study was to establish the feasibility of a Kenyan emergency department (ED)-based sexual assault centre; and to improve knowledge of the characteristics of sexual assault in the region. -
Quality Blood Sampling Techniques and Influence of Socio cultural Factors among ARVs Forces Community in Seeking Healthcare
(SMU Medical Journal, 2016-01)Project monitoring and evaluation (M/E) determines resource accountability and its impact to various stakeholders. Plenary project success requires holistic community participation and empowerment. However, this approach ... -
21 Days of Social Synergistic Pilot Survey on Community Participation to Determine the Level Virulence of COVID-19 in Africa before Re-Opening of the Education Sector in an …
(ACTA SCIENTIFIC MEDICAL SCIENCES, 2020-05)21 days of Synergistic community participation survey [2] to determine reopening of education sector in Africa remain a key cradle to create psycho social confidence in parents, pupils and students since they left school ...