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Hepatitis B and C virus co-infections and genetic diversity among HIV-1 infected individuals in Siaya County, Kenya
(EAST AFRICAN MEDICAL JOURNAL, 2021)
Objectives: The present study determined the prevalence of HBV/HCV coinfections; genetic diversity and drug resistance of HBV among HIV infected
patients visiting Siaya County Referral Hospital, Kenya.
Design: This was ...
Molecular identification and antibiotic susceptibility patterns of bacterial isolates from urine samples of African buffalo, eland and cattle
(International Journal of Applied Biology, 2021)
Presence of antibiotic resistant bacteria in natural environment is an escalating risk of serious implication on human and animal health. Livestock and wildlife have been long recognized as reservoirs for antibiotic resistant ...
Patient care and clinical outcomes for patients with COVID-19 infection admitted to African high-care or intensive care units (ACCCOS): a multicentre, prospective, observational cohort study
(Elsevier, 2021)
Background
Molecular imaging is increasingly used to guide treatment decisions and planning in prostate cancer. We aimed to evaluate the role of 18F-fluciclovine-PET/CT in improving cancer control compared with conventional ...
A ten-year study of Retinoblastoma in Uganda: An approach to improving outcome with limited resources
(Elsevier, 2021)
Background: Survival of children with cancer in resource-limited regions is very poor compared to betterresourced regions. Retinoblastoma (RB) is a childhood cancer that is commonly reported in many regions of
Africa. RB ...
Smartphone-based Ophthalmic Imaging Compared With Spectral-domain Optical Coherence Tomography Assessment of Vertical Cup-to-disc Ratio Among Adults in Southwestern Uganda
(NIH Public Access, 2021)
Precis: Using optical coherence tomography (OCT) measurements as a reference standard for vertical cup-to-disc ratio (vCDR), a smartphone-based ophthalmic camera has a sensitivity of 67.7% and specificity of 96.7% to detect ...
Enhanced postoperative surveillance versus standard of care to reduce mortality among adult surgical patients in Africa (ASOS-2): a cluster-randomised controlled trial
(Elsevier, 2021)
Risk of mortality following surgery in patients across Africa is twice as high as the global average. Most of
these deaths occur on hospital wards after the surgery itself. We aimed to assess whether enhanced postoperat ...
Phytochemistry and insecticidal activity of Annona mucosa leaf extracts against Sitophilus zeamais and Prostephanus truncatus
(Journal of Asian Natural Products Researc, 2021)
A new oleanane type triterpene characterized as 3α, 24-diacetoxy-12-oleanene (1) together with known compounds 2-10, were isolated from Annona mucosa leaf extracts. Their structural elucidation was accomplished using ...
Caffeine for the care of preterm infants in sub- Saharan Africa: a missed opportunity?
(BMJ Specialist Journals, 2021)
In 2019, 2.4 million neonates (infants <28 days of age) died globally. Of these, over 80% were preterm infants (<37 weeks gestation), with the majority born in low- income and middle- income countries.1 Complications of ...
Haematological abnormalities in children with sickle cell disease and non-severe malaria infection in western Kenya
(Springer, 2021)
In Plasmodium falciparum infection, clinical conditions such as anaemia, thrombocytopenia and leukocytosis are common. Mutation in haemoglobin sub-unit beta gene (HBB) may be a genetic factor responsible for these ...
Clinical laboratory hematology reference values among infants aged 1month to 17 months in Kombewa Sub-County, Kisumu: A cross sectional study of rural population in Western Kenya
(Public Library of Science, 2021-03-17)
There is an urgent need for reliable region-specific hematological reference values for clinical monitoring. Laboratory reference ranges are important for assessing study participant
eligibility, toxicity grading and ...