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Clinical predictors of severe malarial anaemia in a holoendemic Plasmodium falciparum transmission area.

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dc.contributor.author Were
dc.contributor.author Novelli, Enrico M
dc.contributor.author Hittner, James B
dc.contributor.author Davenport, GC
dc.contributor.author Ouma, Collins
dc.contributor.author Obaro, Stephen
dc.contributor.author Kaplan, Sandra
dc.contributor.author Ong'echa, JM
dc.contributor.author Perkins, DJ
dc.date.accessioned 2018-01-24T06:19:38Z
dc.date.available 2018-01-24T06:19:38Z
dc.date.issued 2005
dc.identifier.uri https://repository.maseno.ac.ke/handle/123456789/207
dc.description.abstract Severe malarial anaemia (SMA) is a common complication of Plasmodium falciparum infections, resulting in mortality rates that may exceed 30% in paediatric populations residing in holoendemic transmission areas. One strategy for reducing the morbidity and mortality associated with SMA is to identify clinical predictors that can be readily recognized by caregivers for prompt therapeutic interventions. To determine clinical predictors of SMA, Kenyan children (3-36 mos., n= 671) presenting with acute illness at a rural hospital in Siaya District were recruited. Demographic, clinical, laboratory and haematological parameters were measured upon enrolment. Since HIV-1 and bacteraemia promote reduced haemoglobin (Hb) concentrations, children with these infections were excluded from the analyses. Children with P. falciparum mono-infections (n= 355) were stratified into three … en_US
dc.publisher British Journal of Haematology en_US
dc.title Clinical predictors of severe malarial anaemia in a holoendemic Plasmodium falciparum transmission area. en_US
dc.type Article en_US


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