| dc.description.abstract | Background The spread of mono-resistant and multi-drug resistant tuberculosis (MDR-TB)
has been enhanced by delays in the identification of resistant strains. However, resistance
gene patterns and the extent and distribution of mono-resistant TB and MDR-TB is unknown,
particularly for western Kenya where Human Immunodeficiency Virus (HIV) is common. As
such, the overall objective of the current study was to identify cases of mono-resistant TB
and MDR-TB among enrolled patients in health facilities in western Kenya. Methods Patients
with a suspected TB history were referred by clinicians to the health facilities for TB and HIV
diagnosis. HIV testing was done using the Unigold and Abbott Determine kits. Early morning
sputum samples were collected and cultured on Mycobacteria growth indicator tubes (MGIT)
and incubated at 37° C. Drug susceptibility testing (DST) using the SIRE® kit was done … | en_US |
