Department of Public Health: Recent submissions
Now showing items 181-200 of 257
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Perceived occupational risk of infection among hospital mortuary attendants in Nyanza Province, Kenya
(Int J Innov Res Stud, 2014)Introduction: A high proportion of the estimated 1.7 million people who die annually in Kenya occur in hospital settings and are laid in a mortuary before burial. Nyanza Province has a high morbidity and mortality rate, ... -
Morbidity and CD4+ Cell Counts at Initial Presentation of a Cohort of HAART-Naive, HIV Positive Kenyan Patients: Implications to Initiating HAART
(University of Nairobi, 2014)Background: Sub-Saharan Africa with under 10% of the worldfs total population accounts for 60-70% of all HIV/AIDS cases. While these patients require HAART to manage the disease, HAART is not universally available. ... -
Shorter interval and multiple flooding-drying cycling enhanced the mineralization of 14C-DDT in a paddy soil
(Elsevier, 2019-08-01)DDT and its main metabolites (DDTs) are still the residual contaminants in soil. Sequential anaerobic-aerobic cycling has long been approved for enhancing the degradation of DDTs in soil. However, there is a lack of study ... -
Diversity of brucellosis and multi-strain co-infection in a transboundary livestock production system between Tanzania and Kenya
(AAS Open Res, 2019-08-05)Objective: Brucellosis is a debilitating zoonotic disease affecting humans and animals with high prevalence in Kenya and Tanzania. This study was conducted to detect and identify the Brucella species circulating in various ... -
The Role of Participatory Learning and Action on Strengthening the Different Domains of Empowerment on Self-medication with Antimicrobials in Nyalenda Informal Settlement, Kisumu County, Kenya
(Journal of Advances in Medical and Pharmaceutical Sciences, 2019-08-30)Self-medication with antimicrobials (SMWA) is a common global practice. Studies in Nyalenda B Ward, an informal settlement in western Kenya, found that significant households (76.6%) perceived the practice of SMWA as ... -
Cyclooxygenase-2 haplotypes influence the longitudinal risk of malaria and severe malarial anemia in Kenyan children from a holoendemic transmission region
(Nature Publishing Group, 2020-01)Cyclooxygenase-2 [(COX-2) or prostaglandin endoperoxide H2 synthase-2 (PTGS-2)] induces the production of prostaglandins as part of the host-immune response to infections. Although a number of studies have demonstrated the ... -
Nutritional service needs of pregnant and lactating adolescent girls in trans-Mara east Sub-County, Narok County: focus on access and utilization of nutritional advice and services
(BioMed Central, 2019-12)Background An understanding of the association between adolescent nutrition, adolescent pregnancy and their quest for healthcare services may elucidate a basis for intervention and formulation of programs that enhance ... -
Genetic variation in interleukin-7 is associated with a reduced erythropoietic response in Kenyan children infected with Plasmodium falciparum
(BioMed Central, 2019-12-01)Severe malarial anemia (SMA) is a leading cause of malaria-related morbidity and mortality in children. The genetic factors that influence development of SMA and inefficient erythropoiesis, a central pathogenic feature of ... -
Socio-demographic and facility-based determinants of perceived quality of nutrition Services of Pregnant and Lactating Adolescent Girls in Trans-Mara east Sub-County, Narok County, Kenya
(BioMed Central, 2019-12-01)Background: It has been established that use and utilization of nutrition services among adolescents are highly linked to availability, access, cost and quality of care. The main objective of this study was to assess the ... -
Acceptability, adherence, and clinical outcomes, of amoxicillin dispersible tablets versus oral suspension in treatment of children aged 2–59 Months with pneumonia, Kenya: A cluster randomized controlled trial
(Elsevier, 2020-04-01)Amoxicillin dispersible tablet (DT) is now recommended by the WHO as a first-line drug for the treatment of pneumonia in children below 5 years. The study aim was to compare acceptability, adherence and clinical outcome ... -
Socio-economic impacts of brucellosis on livestock production and reproduction performance in Koibatek and Marigat regions, Baringo County, Kenya
(BioMed Central, 2020)Abstract Background Brucellosis in Africa is caused by Brucella species transmitted through contaminated or contacts with infected animals or their carcasses. The disease reduces livestock production and reproduction ... -
Serological and molecular evidence of Brucella species in the rapidly growing pig sector in Kenya
(2020)Abstract Background: Brucellosis is an emerging yet neglected zoonosis that has been reported in Kenya. Epidemiological data on brucellosis in ruminants is readily accessible; however, reports on brucellosis in pigs ... -
Power dynamics as a determinant of access and utilization of nutrition services by pregnant and lactating adolescent girls in Trans-Mara East Sub-County, Narok County, Kenya
(2020-06-12)Abstract Background: During pregnancy or lactating, adequate nutrition for adolescents becomes critical to reduce risks for both child and maternal-related morbidity and mortality. Power dynamics play a massive role in ... -
Influence of blood group, Glucose-6-phosphate dehydrogenase and Haemoglobin genotype on Falciparum malaria in children in Vihiga highland of Western Kenya
(BioMed Central, 2020-07-09)Genetic diversity of ABO blood, glucose-6-phosphate dehydrogenase (G6PD) deficiency and haemoglobin type and their ability to protect against malaria vary geographically, ethnically and racially. No study has been carried ... -
Haplotypes of IL12B promoter polymorphisms condition susceptibility to severe malaria and functional changes in cytokine levels in Thai adults
(Immunogenetics, 2012)Polymorphic variability in immune response genes, such as IL12B, encoding the IL-12p40 subunit is associated with susceptibility to severe malaria in African populations. Since the role of genetic variation in conditioning ... -
Polymorphic Variability in the Interleukin (IL)-1Beta Promoter Conditions Susceptibility to Severe Malarial Anemia and Functional Changes in IL-1Beta Production
(PubMed, 2012)Interleukin (IL)-1beta is a cytokine released as part of the innate immune response to Plasmodium falciparum. Because the role played by IL-1beta polymorphic variability in conditioning the immunopathogenesis of severe ... -
Functional promoter haplotypes of interleukin-18 condition susceptibility to severe malarial anemia and childhood mortality.
(PubMed, 2012)Severe malarial anemia (SMA) is a leading cause of morbidity and mortality in children residing in regions where plasmodium falciparum transmission is holoendemic. Although largely unexplored in children with SMA, ... -
MIF (macrophage migration inhibitory factor) promoter polymorphisms and susceptibility to severe malarial anemia
(Journal of Infectious Diseases, 2012)Severe malarial anemia (SMA) resulting from Plasmodium falciparum infection is one of the leading causes of childhood mortality in sub-Saharan Africa. The innate immune mediator macrophage migration inhibitory factor ... -
Functional Haplotypes of Fc Gamma (Fcy) Receptor (FcyRIIA and FcyRIIB) Predict Risk to Repeated Episodes of Severe Malarial Anaemia and Mortality in Kenyan...
(SN Konah, 2012)Development of protective immunity against Plasmodium falciparum is partially mediated through binding of malaria-specific IgG to Fc gamma (γ) receptors. Variations in human FcγRIIA-H/R-131 and FcγRIIIB-NA1/NA2 affect ... -
Social and Demographic Characteristics of HIV-Positive Mother-Infant Pair and Their Association with Mother-To-Child Transmission of HIV in Vihiga, Kakamega, Bu...
(2012)The World Health Organization report indicates that in 2013~ 35 million people worldwide lived with HIV and AIDS. Of these, 3.2 million were children age< 15 years. The proportion of women living with HIV has remained ...