Journal Articles: Recent submissions
Now showing items 2881-2900 of 4120
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Population-specific evolution of HIV Gag epitopes in genetically diverged patients
(Elsevier, 2013-06-01)Under the host selection pressure HIV evolves rapidly to override crucial steps in the antigen presentation pathway. This allows the virus to escape binding and recognition by cytotoxic T lymphocytes. Selection pressures ... -
HIV-1 progression links with viral genetic variability and subtype, and patient’s HLA type: analysis of a Nairobi-Kenyan cohort
(Springer Berlin Heidelberg, 2014-02-01)In a Nairobi-Kenyan cohort of 50 HIV-1 positive patients, we analysed the prevalence of HIV-1 subtypes and human leucocyte antigen (HLA) alleles. From this cohort, 33 patients were selected for the analysis of HIV-1 infection ... -
Measurement of improvement achieved by participation in international laboratory accreditation in sub-Saharan Africa: the Aga Khan University Hospital Nairobi experience
(Oxford University Press, 2014-02-02)As part of the ISO 15189:2007 accreditation process, the Aga Khan University Hospital Nairobi laboratory became the first internationally accredited hospital laboratory in sub-Saharan Africa outside South Africa in 2011 ... -
Family history as a risk for early-onset type 2 diabetes in Kenyan patients.
(EBSCO Industries, Inc, 2014)Early-onset type 2 diabetes is regarded as disease occurring before the age of 40 years. It is well described, and increasing in prevalence, but there is little information from Africa. We therefore assessed the prevalence ... -
Prevalence of transmitted drug resistance mutations in HIV-1-infected drug-naive patients from urban and suburban regions of Kenya
(Mary Ann Liebert, Inc., 2016-03-01)HIV was first described in Kenya in 1984–1985. Currently, Kenya has an estimated HIV-1 prevalence of 6.2%. With the introduction of antiretroviral drugs, the survival of most HIV patients has been prolonged markedly. ... -
Comparison of equations for estimating glomerular filtration rate in screening for chronic kidney disease in asymptomatic black Africans: a cross sectional study
(BioMed Central, 2017-12)Several equations have been developed to estimate glomerular filtration rate (eGFR). The common equations used were derived from populations predominantly comprised of Caucasians with chronic kidney disease (CKD). Some of ... -
Metabolic syndrome and its predictors in an urban population in Kenya: a cross sectional study
(BioMed Central, 2017-12-01)The metabolic syndrome (MetS) is a clustering of interrelated risk factors which doubles the risk of cardio-vascular disease (CVD) in 5–10 years and increases the risk of type 2 diabetes 5 fold. The identification of ... -
Complete blood count reference intervals from a healthy adult urban population in Kenya
(Public Library of Science, 2018-06-07)There are racial, ethnic and geographical differences in complete blood count (CBC) blood count (CBC) and therefore it is necessary to establish RIs that are population specific. Several studies have been carried out in ... -
Vitamin D status in healthy black African adults at a tertiary hospital in Nairobi, Kenya: a cross sectional study
(BioMed Central, 2018-12-01)Vitamin D has been known since the twentieth Century for its benefits in bone health. Recent observational studies have demonstrated its benefits in infectious diseases such as tuberculosis and non-communicable diseases ... -
Determination of reference intervals for common chemistry and immunoassay tests for Kenyan adults based on an internationally harmonized protocol and up-to-date statistical methods
(Public Library of Science, 2020-07-09)Due to a lack of reliable reference intervals (RIs) for Kenya, we set out to determine RIs for 40 common chemistry and immunoassay tests as part of the IFCC global RI project. -
Effect of anthropogenic activities on physico-chemical parameters and benthic macroinvertebrates of Mara river tributaries, Kenya
(2014)The impact of anthropogenic activities within Bomet and Mulot towns on water quality of Amala and Nyangores tributaries of Mara River, Kenya was assessed using a combination of solid waste, physico-chemical parameters ... -
Intensity of farmland cultivated and soil bulk density in different physiographic units in Nyakach district
(Journal Of Humanities And Social Science, 2014)A number of scholars agree that frequent cultivation raises soil bulk density through compaction and destruction of soil structure. However, no research has been conducted to establish how the intensity of farmland cultivated ... -
Effects of physiographic units on the relationship between cropping frequency and level of soil erosion in Nyakach District, Kenya.
(International Journal of Scientific & Technology Research, 2014)A number of scholars agree that farms which are cropped more frequently tend to exhibit lower levels of soil erosion than those that are cropped less frequently or left fallow. However, the effects of physiographic units ... -
Influence of Water Availability on Food Crop Production in Semi-Arid Areas in Kibwezi District, Makueni County, Kenya
(Arts Humanit, 2015)Ecosystems provide essential services like water regulation and other processes which sustain and fulfill human life by directly or indirectly supporting humans‟ survival and quality of life. However, there is insufficient ... -
Determinants of aboveground carbon offset additionality in plantation forests in a moist tropical forest in western Kenya
(Elsevier, 2016-04-01)Few studies have attempted to identify factors that contribute to aboveground carbon offset additionality in forest restoration planting in the tropics. Moreover, those that have compared aboveground carbon offset potential ... -
Effects of Locations On-and Off-Epigeal Termitaria on Vegetation Lifeforms in Katolo Sub-Location of Kisumu County, Kenya
(SCIRJ, 2017)Epigeal termitaria host richer vegetation assemblages ascribed partly to their elevated nutrients levels in savannah ecosystems. However, elaborate quantitative description of how abundance of various vegetation lifeforms ... -
General analytical solution for the one dimensional regular Cauchy problem of Euler-Poisson-Darboux equation
(Hikari Ltd, 2017)A general analytical solution to the one dimensional regular Cauchy problem of Euler-Poisson-Darboux (EPD) equation has been investigated. The one dimensional EPD which is a Partial Differential Equation (PDE) with initial ... -
The Acoustic Wave Propagation Equation: Discontinuous Galerkin Time Domain Solution Approach
(Hikari Ltd, 2019)This paper discusses a finite element method, discontinuous Galerkin time domain approach that solves the 2-D acoustic wave equation in cylindrical coordinates. The method is based on discretization of the wave field ... -
Improved biodegradation of 1,2,4-trichlorobenzene by adapted microorganisms in agricultural soil and in soil suspension cultures
(Pedosphere, 2011)Inoculating soil with an adapted microbial community is a more effective bioaugmentation approach than inoculation with pure strains in bioremediation. However, information on the potential of different inocula from sites ... -
Enhancement of degradation of DDT and HCB in tropical clay soils in model experiments
(Technische Universität München, 2010)This study sought to enhance the degradation of two persistent organic pollutants (POPs) – DDT and HCB – in two tropical clay soils in model laboratory experiments. Anaerobic-aerobic cycles and amendment with compost were ...