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Functional haplotypes of Fc gamma (Fcγ) receptor (FcγRIIA and FcγRIIIB) predict risk to repeated episodes of severe malarial anemia and mortality in Kenyan children.
(Pub Med Central, 2012-02)
Development of protective immunity against Plasmodium falciparum is partially mediated through binding of malaria-specific IgG to Fc gamma (γ) receptors. Variation in human FcγRIIA-H/R-131 and FcγRIIIB-NA1/NA2 affect ...
Reduced interferon (IFN)-α conditioned by IFNA2 (-173) and IFNA8 (-884) haplotypes is associated with enhanced susceptibility to severe malarial anemia and longitudinal all-cause mortality
(Pub Med Central, 2012-08)
Severe malarial anemia (SMA) is a leading cause of pediatric morbidity and mortality in holoendemic Plasmodium falciparum transmission areas. Although dysregulation in cytokine production is an important etiology of SMA, ...
Reduced Systemic Bicyclo-Prostaglandin-E2 and Cyclooxygenase-2 Gene Expression are Associated with Inefficient Erythropoiesis and Enhanced Uptake of Monocytic Hemozoin in Children with Severe Malarial Anemia
(Pub Med Central, 2012-08)
In holoendemic Plasmodium falciparum transmission areas, severe malaria primarily occurs in children <48 mos. and manifests as severe malarial anemia [SMA; hemoglobin (Hb)<6.0 g/dL]. Induction of high levels of prostaglandin-E2 ...
Functional Haplotypes of Fc Gamma (Fcy) Receptor (FcyRIIA and FcyRIIB) Predict Risk to Repeated Episodes of Severe Malarial Anaemia and Mortality in Kenyan...
(SN Konah, 2012)
Development of protective immunity against Plasmodium falciparum is partially mediated
through binding of malaria-specific IgG to Fc gamma (γ) receptors. Variations in human
FcγRIIA-H/R-131 and FcγRIIIB-NA1/NA2 affect ...