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Factors associated with non-adherence to Artemisinin-based combination therapy (ACT) to malaria in a rural population from holoendemic region of western Kenya.
(Pub Med Central, 2012-06)
Background
Over the years, reports implicate improper anti-malarial use as a major contributor of morbidity and mortality amongst millions of residents in malaria endemic areas, Kenya included. However, there are limited ...
Functional haplotypes of Fc gamma (Fcγ) receptor (FcγRIIA and FcγRIIIB) predict risk to repeated episodes of severe malarial anemia and mortality in Kenyan children.
(Pub Med Central, 2012-02)
Development of protective immunity against Plasmodium falciparum is partially mediated through binding of malaria-specific IgG to Fc gamma (γ) receptors. Variation in human FcγRIIA-H/R-131 and FcγRIIIB-NA1/NA2 affect ...
Functional promoter haplotypes of interleukin-18 condition susceptibility to severe malarial anemia and childhood mortality
(Pub Med Central, 2011-12)
Severe malarial anemia (SMA) is a leading cause of morbidity and mortality in children residing in regions where Plasmodium falciparum transmission is holoendemic. Although largely unexplored in children with SMA, ...
Polymorphic variability in the 3' untranslated region (UTR) of IL12B is associated with susceptibility to severe anaemia in Kenyan children with acute Plasmodium falciparum malaria
(Pub Med Central, 2011-08)
BACKGROUND: Plasmodium falciparum malaria remains a leading cause of morbidity and mortality among African children. Innate immunity provides the first line of defence against P. falciparum infections, particularly in young ...
Association between Fcγ receptor IIA, IIIA and IIIB genetic polymorphisms and susceptibility to severe malaria anemia in children in western Kenya.
(BMC infectious diseases, 2017-04)
BACKGROUND:
Naturally-acquired immunity to Plasmodium falciparum malaria develops after several episodes of infection. Fc gamma receptors (FcγRs) bind to immunoglobulin G (IgG) antibodies and mediate phagocytosis of ...
(−7402 T/G and -4729G/A) condition susceptibility to pediatric severe malarial anemia but not circulating IL-13 levels
(Bio Med Central, 2013)
In holoendemic Plasmodium falciparum transmission areas such as western Kenya, severe malarial anemia [SMA, hemoglobin (Hb) < 6.0 g/dL, with any density parasitemia] is the most common clinical manifestation of severe ...
Comparison of Amplicor HIV-1 DNA Test version 1.5 and Cobas AmpliPrep/Cobas TaqMan HIV-1 Qual test PCR assays for the diagnosis of HIV among HIV expose...
(2015)
In Kenya PCR solutions are available for HIV diagnosis. However few studies
have evaluated existing HIV diagnosis and determined the prevalence of HIV infection in
infants resident in disease endemic regions of western ...
A Model on the Impact of Treating Typhoid with Anti-malarial: Dynamics of Malaria Concurrent and Co-infection with Typhoid
(2015)
International Journal of Mathematical Analysis Vol. 9, 2015, no. 11, 541 - 551 HIKARI Ltd,
www.m-hikari.com http://dx.doi.org/10.12988/ijma.2015.412403 … A Model on the Impact of
Treating Typhoid with … Department ...
Correlates of Behavior Management Strategies Among Learners With Autistic Spectrum Disorders In Primary Schools In Western Kenya
(2014)
Practitioners handling learners with Autistic Spectrum Disorders (ASDs) often feel ill-
prepared to effectively manage this disorder. Quite often, when faced with cases of
challenging behaviour, teachers use coping ...
Modelling the Impact of Misdiagnosis and Treatment on the Dynamics of Malaria Concurrent and Co-infection with Pneumonia
(2013)
Incidences of misdiagnosis of diseases with similar symptoms as malaria has
increased lately due to the increasing levels of endemicity of these diseases and their co-
infection with malaria. In this paper a mathematical ...