School of Public health & Community Development: Recent submissions
Now showing items 61-80 of 402
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Susceptibility of Anopheles gambiae complex mosquitoes to microbial larvicides in diverse ecological settings in western Kenya. Med Vet Entomol
(Wiley, 2019)The microbial larvicidesBacillus thuringiensisvar.israelensis(Bti) andBacillus sphaericus(Bs) (Bacillales: Bacillaceae) are well known for their efficacy andsafety in mosquito control. In order to assess their potential ... -
The diagnostic accuracy of Th1 (IFN-γ, TNF-α, and IL-2) and Th2 (IL-4, IL-6 and IL-10) cytokines response in AFB microscopy smear negative PTB- HIV co-infected patients
(Springer, 2019)Acid Fast Bacilli (AFB) microscopy smear remains the most widely used laboratory diagnostic technique for Pulmonary Tuberculosis (PTB) in low-and-middle income countries. Although it is highly specifc, the sensitivity ... -
Mapping geographic clusters of new HIV diagnoses to inform granular-level interventions for HIV epidemic control in western Kenya
(BMC Public Health, 2021)As countries make progress towards HIV epidemic control, there is increasing need to identify finer geographic areas to target HIV interventions. We mapped geographic clusters of new HIV diagnoses, and described factors ... -
Low sensitivity of the careHPV™ Assay for detection of Oncogenic Human Papillomavirus in cervical samples from HIV-infected and HIV-uninfected Kenyan women
(HSPC, 2020)Human papillomavirus (HPV) infection causes cervical cancer (CC), a common malignancy among Kenyan women. New CC screening methods rely on oncogenic HPV (“highrisk”, or HR-HPV) detection, but most have not been evaluated ... -
Incidence of Brucella infection in various livestock species raised under the pastoral production system in Isiolo County, Kenya
(Springer, 2021)We implemented a longitudinal study to determine the incidence of Brucella infection in cattle, camels, sheep and goats that were being raised in a pastoral area in Isiolo County, Kenya. An initial cross-sectional survey ... -
Phylogeography and population structure of the tsetse fly Glossina pallidipes in Kenya and the Serengeti ecosystem
(PLOS, 2020)Glossina pallidipes is the main vector of animal African trypanosomiasis and a potential vector of human African trypanosomiasis in eastern Africa where it poses a large economic burden and public health threat. Vector ... -
Rethinking the economic costs of hospitalization for malaria: accounting for the comorbidities of malaria patients in western Kenya
(Springer, 2021)Malaria causes significant mortality and morbidity in sub-Saharan Africa, especially among children under five years of age and places a huge economic burden on individuals and health systems. While this burden has been ... -
Challenges Faced by House-Hold Contacts of Pulmonary Tuberculosis Patients In An Urban Setting In Nairobi, Kenya
(2021)Close contacts of active pulmonary tuberculosis (PTB) patients are at higher risk of infection as the confirmed cases remain highly infectious before and while in the early stages of treatment. This work highlights the ... -
Gaps between Knowledge and Malaria Treatment Practices after Intensive Anti-Malaria Campaigns in Western Kenya: 2004–2016
(American Journal of Tropical Medicine & Hygiene, 2020)Effective case management is central for malaria control, but not all of those affected by malaria have access to prompt, effective treatment. In Kenya, free malaria treatment has been implemented since 2006. However, questions ... -
Determinants of tuberculosis treatment interruption among patients in Vihiga County, Kenya
(PLOS ONE, 2021)Despite robust Tuberculosis (TB) program with effective chemotherapy and high coverage, treatment interruption remains a serious problem. Interrupting TB treatment means that patients remain infectious for longer time ... -
Patient’s Characteristics that Influence Provider Initiated HIV Testing and Counselling Service Uptake in Siaya County, Western Kenya
(Asian Journal of Research in Nursing and Health, 2021)Human Immunodeficiency Virus (HIV) / Acquired Immunodeficiency Syndrome (AIDS) contributes 29.3% of all deaths in Kenya and is among leading causes of mortality in the Country. Kenya National HIV prevalence is at 4.9% ... -
Synergism in Antiplasmodial Activities of Artemether and Lumefantrine in Combination with Securidaca longipedunculata Fresen (Polygalaceae)
(MDPI, 2021)Malaria is the most lethal parasitic disease in the world. The frequent emergence of resistance by malaria parasites to any drug is the hallmark of sustained malaria burden. Since the deployment of artemisinin-based ... -
Immunohistochemical Analysis of Prostein Expression in Archived Prostatic Core Biopsies from Prostate Cancer Patients in Western Kenya
(Research Square, 2021)Prostate cancer is the leading cause of cancer-associated mortality in men. Most of the current biomarkers for detection of the disease have low sensitivity and specificity. Prostein is a newly reported prostate cancer ... -
Hyper-prevalence of submicroscopic Plasmodium falciparum infections in a rural area of western Kenya with declining malaria cases
(Springer, 2021)The gold standard for diagnosing Plasmodium falciparum infection is microscopic examination of Giemsa-stained peripheral blood smears. The effectiveness of this procedure for infection surveillance and malaria control may ... -
Effects of Achyranthes aspera, Bidens pilosa and Ajuga remota Leaf extracts on the blood glucose levels and hemoparameters in male goats treated with Alloxan
(AJOL, 2021)Diabetes mellitus is a potentially morbid condition with high prevalence worldwide thus the disease constitutes a major health concern. Presently, it is an incurable metabolic disorder which affects about 2.8% of the global ... -
Effects of Public Health Interventions on Intestinal Parasitic Infections among School-Going Children in Murang’a County, Kenya,
(AJOL, 2021)WHO indicates that intestinal parasitic infections form at least of a quarter of all human infections globally, affecting at least 2 billion people. School-going children are the worst affected by these infections with ... -
Influence of blood meal and age of mosquitoes on susceptibility to pyrethroids in Anopheles gambiae from Western Kenya
(Springer nature, 2019)Physiological characteristics (age and blood feeding status) of malaria vectors can influence their susceptibility to the current vector control tools that target their feeding and resting behaviour. To ensure the ... -
Comprehensive Transcriptome and Mutational Profiling of Endemic Burkitt Lymphoma Reveals EBV Type–Specific Differences
(OnlineFirst, 2017)e most common pedi atric cancer in malaria-endemic equatorial Africa and nearly always contains Epstein–Barr virus (EBV), unlike sporadic Burkitt lymphoma (sBL) that occurs with a lower incidence in developed countries. ... -
Knowledge, Perceptions, and Practice of Nurses on Surveillance of Adverse Events following Childhood Immunization in Nairobi, Kenya
(Hindawi Publishing Corporation, 2016)Although vaccines currently approved for routine childhood immunization are safe and effective, frequent adverse events following immunization often cause illnesses and sometimes loss of public trust in immunization ... -
The impact of long-lasting microbial larvicides in reducing malaria transmission and clinical malaria incidence: study protocol for a cluster randomized controlled trial
(BioMed Central, 2016)The massive scale-up of insecticide-treated nets (ITNs) and indoor residual spraying (IRS) has led to a substantial increase in malaria vector insecticide resistance as well as in increased outdoor transmission, both of ...