School of Public health & Community Development: Recent submissions
Now showing items 361-380 of 402
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Dose-Effects of Bednets Impregnated with a Natural Pyrethrins Formulation: Persistence, Feeding Inhibition, and Wash Resistance against Anopheles gambiae ss
(2012)This study evaluated dose-response, persistence, irritancy and wash resistance of mosquito nets treated with a synergized natural pyrethrins-formulation against Anopheles gambiae ss Methods. Multi-filament polyester ... -
Polymorphisms in Fc gamma receptor (FcγRIIIA-176 F/V) and Toll-like receptor (TLR9 [-1237 T/C]) are associated with protection against severe malarial anemia an...
(American Society for Microbiology, 2012-10-08)Understanding the immunogenetic basis of naturally acquired immunity to Plasmodium falciparum infection would aid in designing a rationally-based malaria vaccine. Variants within the Fc gamma receptors (FcγRs) mediate ... -
Communicating African spirituality through ecology: Challenges and prospects for the 21st century
(2012-06-19)This review was set in the context of African spirituality and ecology. Specifically, the review addressed issues of African spirituality and the environment from a Kenyan context. Through analyses on existing literature, ... -
Provider knowledge of treatment policy and dosing regimen with artemether-lumefantrine and quinine in malaria-endemic areas of western Kenya
(BioMed Central, 2012-12-29)Due to widespread anti-malarial drug resistance in many countries, Kenya included, artemisinin-based Combination Therapy (ACT) has been adopted as the most effective treatment option against malaria. Artemether-lumefantrine ... -
Functional Haplotypes of Fc gamma (Fcγ) receptor (FcγRIIA and FcγRIIIB) predict risk to repeated episodes of severe malarial anemia and mortality in Kenyan children
(Springer-Verlag, 2012-02-01)Development of protective immunity against Plasmodium falciparum is partially mediated through binding of malaria-specific IgG to Fc gamma (γ) receptors. Variations in human FcγRIIA-H/R-131 and FcγRIIIB-NA1/NA2 affect ... -
Effectiveness of Out-patient Therapeutic Program on Nutrition among Under Fives: A Retrospective Study of Kisumu East District, Kenya
(2013)Abstract Outpatient Therapeutic Program (OTP) has been implemented with great success. Monitoring and evaluation against program objectives is integral. This study aimed to assess effectiveness of OTP program in Kisumu ... -
(− 7402 T/G and-4729G/A) condition susceptibility to pediatric severe malarial anemia but not circulating IL-13 levels
(Bio Med Central, 2013)In holoendemic Plasmodium falciparum transmission areas such as western Kenya, severe malarial anemia [SMA, hemoglobin (Hb)< 6.0 g/dL, with any density parasitemia] is the most common clinical manifestation of severe ... -
EBNA-1 specific effector T cell deletion associated with holoendemic malaria exposure in the etiology of endemic Burkitt’s lymphoma (P3063)
(American Association of Immunologists, 2013-05-01)Etiological mechanism of eBL remain largely unknown despite long-standing epidemiological link between malaria and EBV co-infection. Age-dependent deficiency in EBV-specific CD8+ T cell-mediated IFN-γ immunosurveillance ... -
Factors in the management of feeding in nursery school children as perceived by their mothers in rural Bondo County, Kenya
(BioMed Central, 2013-11-15)The effects of malnutrition on health status and survival of children has been the subject of extensive research for several decades. Malnutrition affects physical growth, cognitive development of children, morbidity ... -
Modelling the Impact of Misdiagnosis and Treatment on the Dynamics of Malaria Concurrent and Co-infection with Pneumonia
(2013)Incidences of misdiagnosis of diseases with similar symptoms as malaria has increased lately due to the increasing levels of endemicity of these diseases and their co- infection with malaria. In this paper a mathematical ... -
Correlates of Behavior Management Strategies Among Learners With Autistic Spectrum Disorders In Primary Schools In Western Kenya
(2014)Practitioners handling learners with Autistic Spectrum Disorders (ASDs) often feel ill- prepared to effectively manage this disorder. Quite often, when faced with cases of challenging behaviour, teachers use coping ... -
Efficacy of long lasting insecticidal nets compromised by insecticide resistance
(Research Information Ltd, 2014-01-01)Malaria control is heavily reliant on the use of insecticides given that the two most common control tools, long lasting insecticidal nets (LLIN) and indoor residual sprays are both insecticide based. Of these, the ... -
Systematic Monitoring of Male Circumcision Scale-Up in Nyanza, Kenya: Exploratory Factor Analysis of Service Quality Instrument and Performance Ranking
(Public Library of Science, 2014-07-01)Background Considerable conceptual and operational complexities related to service quality measurements and variability in delivery contexts of scaled-up medical male circumcision, pose real challenges to monitoring ... -
A non-synonymous polymorphism in IL-23R Gene (rs1884444) is associated with reduced risk to schistosomiasis-associated Immune Reconstitution Inflammatory S...
(BioMed Central, 2014-06-10)Background Human Immunodeficiency Virus (HIV) and Schistosomiasis co-infection is common among residents at the shores of Lake Victoria in Kenya. About 36% of this population initiating antiretroviral therapy (ART) ... -
Clinical chemistry profiles in injection heroin users from Coastal Region, Kenya
(Biomed central, 2014-07-09)Background Although the co-burden of injection drug use and HIV is increasing in Africa, little is known about the laboratory markers of injection drug use and anti-retroviral treatment (ART) in Kenyan injection drug ... -
Interleukin-6 and interleukin-10 gene promoter polymorphisms and risk of endemic Burkitt lymphoma
(The American Society of Tropical Medicine and Hygiene, 2014-09-03)Overexpression of interleukin-6 (IL-6) and IL-10 in endemic Burkitt lymphoma (eBL) may facilitate tumorigenesis by providing a permissive cytokine milieu. Promoter polymorphisms influence interindividual differences ... -
Serratia marcescens is injurious to intestinal epithelial cells
(Taylor & Francis, 2014-11-02)Diarrhea causes substantial morbidity and mortality in children in low-income countries. Although numerous pathogens cause diarrhea, the etiology of many episodes remains unknown. Serratia marcescens is incriminated ... -
Changes in antigen-specific cytokine and chemokine responses to Plasmodium falciparum antigens in a highland area of Kenya after a prolonged absence of malari...
(American Society for Microbiology, 2014-09-01)Individuals naturally exposed to Plasmodium falciparum lose clinical immunity after a prolonged lack of exposure. P. falciparum antigen-specific cytokine responses have been associated with protection from clinical ... -
Seroprevalence of anti-dengue virus 2 serocomplex antibodies in out-patients with fever visiting selected hospitals in rural parts of western Kenya in 2010-2011: a cr...
(African Field Epidemiology Network, 2014)There has been a recent increase in the spread of dengue to rural areas. Rural parts of western kenya are naturally prone to mosquito-borne diseases, however, limited research has been documented on infections with ... -
Sickle cell trait is not associated with endemic Burkitt lymphoma: An ethnicity and malaria endemicity‐matched case–control study suggests factors controlling EBV...
(2014-02)Endemic Burkitt lymphoma (eBL) is associated with Epstein–Barr virus (EBV) and Plasmodium falciparum coinfections. Malaria appears to dysregulate immunity that would otherwise control EBV, thereby contributing to eBL ...