School of Public health & Community Development: Recent submissions
Now showing items 121-140 of 402
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Integrative microRNA and mRNA deep-sequencing expression profiling in endemic Burkitt lymphoma
(Springer, 2017)Burkitt lymphoma (BL) is characterized by overexpression of the c-myc oncogene, which in the vast majority of cases is a consequence of an IGH/MYC translocation. While myc is the seminal event, BL is a complex amalgam of ... -
Acceptable food products processed from underutilized crop
(Research Gate, 2017)Underutilized crops are rich in micronutrients but are only cultivated at subsistence level (1). Food processing technologies, particularly at household level, are challenging and often not applicable to traditional crops ... -
Assessment of patient satisfaction levels in a County Referral Hospital: A case of Busia County Referral Hospital
(Baraton Interdisciplinary Research Journal, 2017)In health care settings, excellence is measured in health outcomes and patient satisfaction. As part of monitoring and evaluation envisioned by health policy framework in Kenya, assessing patient satisfaction is one ... -
Diagnostic utility of zinc protoporphyrin to detect iron deficiency in Kenyan preschool children: a community-based survey
(BMC Hematology, 2017)Zinc protoporphyrin (ZPP) has been used to screen and manage iron deficiency in individual children, but it has also been recommended to assess population iron status. The diagnostic utility of ZPP used in combination ... -
Tumor infiltrating leukocyte density is independent of tumor grade and molecular subtype in aggressive breast cancer of Western Kenya
(Springer, 2017)Tumors commonly are infiltrated by leukocytes, or tumor infiltrating leukocytes (TILs). It remains unclear, however, if the density and type of individual TILs has a direct or simply correlative role in promoting poor ... -
Comparative evaluation of fluorescent in situ hybridization and Giemsa microscopy with quantitative real-time PCR technique in detecting malaria parasites in a holoendemic region of Kenya
(Springer, 2017)arly and accurate diagnosis of malaria is important in treatment as well as in the clinical evaluation of drugs and vaccines. Evaluation of Giemsa-stained smears remains the gold standard for malaria diagnosis, although ... -
Phenotypic and Genotypic Antibiotic Resistant diarrheagenic Escherichia coli pathotypes isolated from Children with Diarrhea in Nairobi City, Kenya
(PMC, 2020)Background: The marked genome plasticity of diarrheagenic Escherichia coli promotes emergence of pathotypes displaying unique phenotypic and genotypic resistance. This study examined phenotypic and genotypic antibiotic ... -
Adaptive interventions for optimizing malaria control: an implementation study protocol for a block-cluster randomized, sequential multiple assignment trial
(BMC, 2020)Background In the past two decades, the massive scale-up of long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) has led to significant reductions in malaria mortality and morbidity. Nonetheless, the ... -
Synergistic blending of high-valued heterocycles inhibits growth of Plasmodium falciparum in culture and P. berghei infection in mouse model
(Scientific Reports, 2017)A series of phthalimide analogues, novelized with high-valued bioactive scaffolds was synthesized by means of click-chemistry under non-conventional microwave heating and evaluated as noteworthy growth inhibitors of ... -
Determinants of Sexual Functionality Among Men Who Utilize Sex Enhancing Drugs
(Canadian Center of Science and Education, 2020)This paper is based on the findings of a study carried out on the determinants of sexual functionality among men who utilize sex enhancing drugs (SEDs). The study was submitted as a thesis in partial fulfillment for the ... -
Rapid Epidemiological Appraisal of Spatial Distribution of Animal Bite Injury Cases and Rabies Post Exposure Prophylaxis in Kisumu County, Kenya
(Research Square, 2020)Animal bites in humans provide an important source of epidemiological information which is crucial in enhancing rabies surveillance in humans and animals. Rabies post exposure prophylaxis consumes substantial resources ... -
Study of Kenyan Optometrists View on Future of Optometry and Prospective Impact on Public Health
(Research Square, 2020)Background: VISION 2020: The Right to Sight, was to ensure that by the year 2020, a great reduction in the incidences of avoidable blindness be recorded. This was achivable by training optometrists. Kenya has a population ... -
Causes of preterm and low birth weight neonatal mortality in a rural community in Kenya: evidence from verbal and social autopsy
(BMC Pregnancy and Child Birth, 2021)Background: Under-fve mortality in Kenya has declined over the past two decades. However, the reduction in the neonatal mortality rate has remained stagnant. In a country with weak civil registration and vital statistics ... -
Rapid Situational Assessment of People Who Inject Drugs (PWID) in Nairobi and Coastal regions of Kenya: A Respondent Driven Sampling Survey
(Research Gate, 2020)Background: A Cross-sectional Rapid Situational Assessment of People Who Inject Drug (PWIDs) applying Respondent Driven sampling techniques (RDS) was used to recruit subjects/participants in a study aimed at assessing ... -
Changes in the frequencies of Plasmodium falciparum dhps and dhfr drug-resistant mutations in children from Western Kenya from 2005 to 2018: the rise of Pfdhps S436H
(BMC, 2020)Background: Sulfadoxine-pyrimethamine (SP) is the only anti-malarial drug formulation approved for intermittent preventive treatment in pregnancy (IPTp). However, mutations in the Plasmodium falciparum dhfr (Pfdhfr) and ... -
Comparison of Microscopy and PCR for Detection of Giardia Lamblia and Entamoeba Histolytica in Human Stool Specimens in a Resource Limited Setting in Western Kenya
(Ethiop J Health Sci, 2020)BACKGROUND፡ Accurate diagnosis of Giardia lamblia and Entamoeba histolytica is important since these intestinal parasites account for a significant proportion of morbidity and mortality globally. Microscopy is the key ... -
Nutrition and growth outcomes are affected by aflatoxin exposures in Kenyan children
(Taylor & Francis, 2020)Aflatoxin exposure, malnutrition and growth impairment in children present significant public health problems in low- and middle-income countries. Recent epidemiology studies show that exposure to aflatoxins through ... -
Caregiver’s Knowledge and Attitude Regarding Care of Schizophrenia at Mathari Teaching and Referral Hospital, Kenya
(American Journal of Psychiatry and Neuroscience, 2018)Schizophrenia is a mental disorder which is a major public health concern since it affects the quality of life of the schizophrenic patient. The patient requires a caregiver to support them in the entire phase of the ... -
Candidate-gene based GWAS identifies reproducible DNA markers for metabolic pyrethroid resistance from standing genetic variation in East African Anopheles gambiae
(Springer, 2018)Metabolic resistance to pyrethroid insecticides is widespread in Anopheles mosquitoes and is a major threat to malaria control. DNA markers would aid predictive monitoring of resistance, but few mutations have been discovered ... -
Assessment of optometrists’ knowledge, skills and practice on cataract: a crosssectional study from Kisumu County, Western Kenya
(BioMed Central, 2020)Background: The quality of life can be impacted negatively by blindness arising from cataract. The total prevalence of blindness in Kenya is estimated at 0.7%, however cataract contributes almost half (43%) of the total ...