School of Public health & Community Development: Recent submissions
Now showing items 1-20 of 402
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Evaluating Antiplasmodial and Antimalarial Activities of Soybean (Glycine max) Seed Extracts on P. falciparum Parasite Cultures and P. berghei-Infected Mice
(Hindawi, 2020-02-17)Plasmodium parasite resistance to artemisinin-based combination therapies (ACTs) calls for development of new, affordable, safe, and effective antimalarial drugs. Studies conducted previously on soybean extracts have ... -
Antimalarial activity of Nigella sativa L. Seed extracts and selection of resistance in Plasmodium berghei ANKA in a mouse model
(Hindawi Limited, 2021-02-03)Chemotherapy plays a crucial role in malaria control. However, the main obstacle to treatment has been the rise of parasite resistance to most antimalarial drugs. Artemisinin-based combination therapies (ACTs) remain the ... -
Perceptions of Faculty Officials on Online Learning in Kenyan Institutions of Higher Education During the COVID-19 Pandemic: A Rapid Qualitative Study
(Emerald Publishing Limited, 2023-11-06)Due to the Coronavirus 2019 (COVID-19) pandemic, education has been disrupted right from kindergarten to University. Globally, states are advocating for online learning. The COVID-19 pandemic had led to the closure of ... -
The Potential of Differentiation Related Gene 1 DRG1) as a Biomarker for Metastasis of Estrogen Receptor Positive Breast Cancer
(Journal of Advances in Medicine and Medical Research, 2021-10-07)Breast cancer is major burden worldwide and the majority of breast cancers express estrogen receptors (ER) suggesting a high dependence on estrogen hormone. Age is among the major determinants of breast cancer development, ... -
Seasonality of associations between production of indigenous foods and food security status of mother-child dyads in Kisumu County, Kenya
(BioMed Central, 2024-01-10)Food insecurity is a major predicament for rural populations, especially mothers and children, whose livelihoods are often dependent on rain-fed agriculture. Indigenous foods have the potential of mitigating food insecurity ... -
Efficacy of the PermaNet Dual compared to the Interceptor G2 and the PermaNet 3.0 in experimental huts in Siaya County, western Kenya.
(Research Square, 2024-01-25)Pyrethroid-chlorfenapyr nets have shown significant epidemiological impact over pyrethroid-only and pyrethroid plus piperonal-butoxide (PBO) in Africa. Here we describe a non-inferiority evaluation of PermaNet Dual, a ... -
Barriers and Misconceptions Hindering Reduction of Intestinal Schistosomiasis in Mbita Sub-County, Western Kenya
(Research Square, 2024-02-05)Community and individual participation are crucial for the success of schistosomiasis control. The World Health Organization (WHO) has highlighted the importance of enhanced sanitation, health education, and mass treatment ... -
Trends of non-vaccination, under-vaccination and missed opportunities for vaccination (2003–2014) amongst children 0–23 months in Kenya
(Public Library of Science, 2024-02-06)Vaccines are effective and cost-effective. Non-vaccination, under-vaccination, and missed opportunities for vaccination (MOV), have contributed to incomplete vaccination coverage in Kenya. Analyzing their trends is essential ... -
Coagulation hallmark indicators of menorrhagia in a comparative study between menorrhagic and healthy women attending Bungoma County Referral Hospital in Kenya
(Research Square, 2024-02-13)Despite the significant burden of menorrhagia among women in Western Kenya, it remains unknown whether coagulation disorders are one of the important underlying causes of this condition in the region. This study evaluated ... -
Availability of quality health information on morbidity and mortality indicators to improve maternal healthcare services in Migori county, Kenya
(International Journal of Social Science and Economic Research, 2022-03-31)Assessing availability of quality health information on maternal morbidity and mortality indicators in the provision of quality healthcare services is critical. The study used retrospective and prospective study designs ... -
Factors influencing patients’ adherence to malaria Artemisinin-based combination therapy treatment in Kamuli District, Uganda
(Research Square, 2023-10-06)Patients’ adherence to prescribed Artemisinin-based Combination Therapy (ACT) treatment is a key malaria control strategy. To accelerate and realize a malaria free country, malaria management measures remain a key public ... -
Food price perception, food and beverage marketing and the nutritional status of children 6–24 months in Obunga slums, Kisumu Kenya: a cross-sectional study
(BioMed Central, 2023)Malnutrition is a significant problem in Africa. In Kenya, 26% of under-fives are stunted; slums are the hardest hit. Obunga slum has the highest prevalence at 40%. A cross-sectional study was adopted; simple random ... -
The role of vitamin D status on treatment outcome among HIV-infected children receiving care in Kisumu County, Kenya
(Researchsquare, 2023-09-19)Kenya has a paediatric HIV burden of nearly 140,000 children, of which only 48% of those on antiretroviral therapy (ART) have achieved the desired viral suppression possibly due to vitamin D deficiency. We explored the ... -
Comparison of Different Trapping Methods to Collect Malaria Vectors Indoors and Outdoors in Western Kenya
(Research square, 2023-08-31)Enhanced vector surveillance, is one of the 4 pillars of the WHO’s global vector control response (2017–2030). Human landing catches are the gold standard for entomological surveys but are difficult to implement and expose ... -
Health Providers’ Self Reported Provision of Preconception Care and Associated Factors in Kisumu County-kenya
(Research square, 2023-09-01)Preconception care (PCC) is the provision of health interventions to women and couples before conception occurs and is valuable in preventing and controlling noncommunicable diseases. In Africa, more so in Kenya, maternal ... -
Human NCR3 gene variants rs2736191 and rs11575837 alter longitudinal risk for development of pediatric malaria episodes and severe malarial anemia
(BioMed Central, 2023-09-13)Plasmodium falciparum malaria is a leading cause of pediatric morbidity and mortality in holoendemic transmission areas. Severe malarial anemia [SMA, hemoglobin (Hb) < 5.0 g/dL in children] is the most common clinical ... -
Exploring Shigella vaccine priorities and preferences: Results from a mixed-methods study in low-and middle-income settings
(Elsevier, 2023-08-09)Shigella is the leading bacterial cause of diarrheal mortality in children and can cause long-term effects on growth and development. No licensed Shigella vaccines currently exist but several promising candidates are in ... -
Finding the missing children for TB care and prevention in Kenya
(International Union Against Tuberculosis and Lung Disease, 2022-12-01)SETTING: One hundred high TB burden facilities in nine counties in Kenya.OBJECTIVES: 1) To increase uptake of TB preventive therapy (TPT) among child contacts aged <5 years, and 2) to increase TB diagnosis in children aged ... -
Hemoglobinopathies, merozoite surface protein-2 gene polymorphisms, and acquisition of Epstein Barr virus among infants in Western Kenya
(BioMed Central, 2023)Epstein Barr virus (EBV)-associated endemic Burkitt’s Lymphoma pediatric cancer is associated with morbidity and mortality among children resident in holoendemic Plasmodium falciparum regions in western Kenya. P. falciparum ... -
Effects of bacterial composition and aquatic habitat metabolites on malaria vector larval availability in irrigated and non-irrigated sites of Homa Bay county, western Kenya
(PLOS ONE, 2023)Gravid Anopheles malaria vectors depend on both chemical and physical (including microbial) cues for selection of preferred habitats for oviposition. This study focused on assessing the effects of bacterial composition ...