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Association between Fcγ receptor IIA, IIIA and IIIB genetic polymorphisms and susceptibility to severe malaria anemia in children in western Kenya
(BioMed Central, 2017-04-20)
Background Naturally-acquired immunity to Plasmodium falciparum malaria develops after
several episodes of infection. Fc gamma receptors (FcγRs) bind to immunoglobulin G (IgG)
antibodies and mediate phagocytosis of ...
Haplotype of non-synonymous mutations within IL-23R is associated with susceptibility to severe malaria anemia in a P. falciparum holoendemic transmission area...
(BioMed Central, 2017-04-20)
Background Improved understanding of the molecular mechanisms involved in pediatric
severe malarial anemia (SMA) pathogenesis is a crucial step in the design of novel
therapeutics. Identification of host genetic ...