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Association between Fcγ receptor IIA, IIIA and IIIB genetic polymorphisms and susceptibility to severe malaria anemia in children in western Kenya
(BioMed Central, 2017-04-20)
Background Naturally-acquired immunity to Plasmodium falciparum malaria develops after
several episodes of infection. Fc gamma receptors (FcγRs) bind to immunoglobulin G (IgG)
antibodies and mediate phagocytosis of ...
(− 7402 T/G and-4729G/A) condition susceptibility to pediatric severe malarial anemia but not circulating IL-13 levels
(Bio Med Central, 2013)
In holoendemic Plasmodium falciparum transmission areas such as western Kenya, severe
malarial anemia [SMA, hemoglobin (Hb)< 6.0 g/dL, with any density parasitemia] is the most
common clinical manifestation of severe ...