Browsing School of Public health & Community Development by Author "Chelimo, Kiprotich"
Now showing items 1-3 of 3
-
EBNA-1 specific effector T cell deletion associated with holoendemic malaria exposure in the etiology of endemic Burkitt’s lymphoma (P3063)
Mulama, David; Chelimo, Kiprotich; Collins, Ouma; Jura, Walter; Otieno, Juliana; Vulule, John; Munz, Christian; Moormann, Ann (American Association of Immunologists, 2013-05-01)Etiological mechanism of eBL remain largely unknown despite long-standing epidemiological link between malaria and EBV co-infection. Age-dependent deficiency in EBV-specific CD8+ T cell-mediated IFN-γ immunosurveillance ... -
Interleukin-6 and interleukin-10 gene promoter polymorphisms and risk of endemic Burkitt lymphoma
Oduor, Cliff I; Chelimo, Kiprotich; Ouma, Collins; Mulama, David H; Foley, Joslyn; Vulule, John; Bailey, Jeffrey A; Moormann, Ann M (The American Society of Tropical Medicine and Hygiene, 2014-09-03)Overexpression of interleukin-6 (IL-6) and IL-10 in endemic Burkitt lymphoma (eBL) may facilitate tumorigenesis by providing a permissive cytokine milieu. Promoter polymorphisms influence interindividual differences ... -
Sickle cell trait is not associated with endemic Burkitt lymphoma: An ethnicity and malaria endemicity‐matched case–control study suggests factors controlling EBV...
Mulama, David H; Bailey, Jeffrey A; Foley, Joslyn; Chelimo, Kiprotich; Ouma, Collins; Jura, Walter G; Otieno, Juliana; Vulule, John; Moormann, Ann M (2014-02)Endemic Burkitt lymphoma (eBL) is associated with Epstein–Barr virus (EBV) and Plasmodium falciparum coinfections. Malaria appears to dysregulate immunity that would otherwise control EBV, thereby contributing to eBL ...