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Now showing items 38-57 of 76

Impact of Four Years of Annual Mass Drug Administration on Prevalence and Intensity of Schistosomiasis among Primary and High School Children in Western Kenya: A Repeated Cross-Sectional Study.

Abudho, Bernard O; Ndombi, Eric M; Guya, Bernard; Carter, Jennifer M; Riner, Diana K; Kittur, Nupur; Karanja, Diana M S; Secor, Evan W; Colley, Daniel G (The American journal of tropical medicine and hygiene, 2018-03-12)

Schistosomiasis remains a major public health problem in Kenya. The World Health Organization recommends preventive chemotherapy with praziquantel (PZQ) to control morbidity due to schistosomiasis. Morbidity is considered ...
Increased severe anemia in HIV-1-exposed and HIV-1-positive infants and children during acute malaria

Were, T; Otieno, Richard O; Ouma, Collins; Ong'echa, JM; Kelle, Christopher C; Waindi, Eliud N; Michaels, Marian G; Day, Richard D; Vulule, John M; Perkins, DJ (AIDS, 2005)

Increased severe anemia in HIV-1-exposed and HIV-1-positive infants and children during acute malaria
Interleukin-6 and interleukin-10 gene promoter polymorphisms and risk of endemic Burkitt lymphoma

Oduor, Cliff I; Chelimo, Kiprotich; Ouma, Collins; Mulama, David H; Foley, Joslyn; Vulule, John; Bailey, Jeffrey A; Moormann, Ann M (The American Society of Tropical Medicine and Hygiene, 2014-09-03)

Overexpression of interleukin-6 (IL-6) and IL-10 in endemic Burkitt lymphoma (eBL) may facilitate tumorigenesis by providing a permissive cytokine milieu. Promoter polymorphisms influence interindividual differences ...
Knowledge and behaviour as determinants of anti-malarial drug use in a peri-urban population from malaria holoendemic region of western Kenya

Watsierah, Carren A; Jura, Walter G; Raballah, Evans; Kaseje, Dan; Abong'o, Benard; Ouma, Collins (BioMed Central, 2011-04-20)

The appropriate use of anti-malarial drugs determines therapeutic efficacy and the emergence and spread of drug-resistant malaria. Strategies for improving drug compliance require accurate information about current ...
MIF (macrophage migration inhibitory factor) promoter polymorphisms and susceptibility to severe malarial anemia

Were, T; Awandare, GA; Martinson, JJ; Ouma, C; Davenport, GC; Ong'echa, JM; Wang, W; L, Leng; RE, Ferrell,; R, Bucala,; DJ, Perkins (Journal of Infectious Diseases, 2012)

Severe malarial anemia (SMA) resulting from Plasmodium falciparum infection is one of the leading causes of childhood mortality in sub-Saharan Africa. The innate immune mediator macrophage migration inhibitory factor ...
A Model on the Impact of Treating Typhoid with Anti-malarial: Dynamics of Malaria Concurrent and Co-infection with Typhoid

Akinyi, Okaka C; Mugisha, JYT; Manyonge, A; Ouma, C; Maseno, Kenya (2015)

International Journal of Mathematical Analysis Vol. 9, 2015, no. 11, 541 - 551 HIKARI Ltd, www.m-hikari.com http://dx.doi.org/10.12988/ijma.2015.412403 … A Model on the Impact of Treating Typhoid with … Department ...
Modelling the Impact of Misdiagnosis and Treatment on the Dynamics of Malaria Concurrent and Co-infection with Pneumonia

Akinyi, Okaka; Mugisha, JYT; Manyonge, A; Ouma, C; Maseno, Kenya (2013)

Incidences of misdiagnosis of diseases with similar symptoms as malaria has increased lately due to the increasing levels of endemicity of these diseases and their co- infection with malaria. In this paper a mathematical ...
Multiple evolutionary origins of Trypanosoma evansi in Kenya

Kamidi, Christine M; Saarman, Norah P; Dion, Kirstin; Mireji, Paul O; Ouma, Collins; Murilla, Grace; Aksoy, Serap; Schnaufer, Achim; Caccone, Adalgisa (Public Library of Science, 2017-09-07)

Trypanosoma evansi is the parasite causing surra, a form of trypanosomiasis in camels and other livestock, and a serious economic burden in Kenya and many other parts of the world. Trypanosoma evansi transmission can ...
MYCOBACTERIUM TUBERCULOSIS RESISTANCE TO ISONIAZID AND RIFAMPICIN IN A HIV-1 ENDEMIC POPULATION IN WESTERN KENYA IN 2014

Likhovole, Clement; Ouma, Collins; Vulule, John; Musau, Susan; Khayumbi, Jeremiah; Okumu, Albert; Murithi, Wilfred (BMJ Specialist Journals, 2017-02-01)

Background The spread of mono-resistant and multi-drug resistant tuberculosis (MDR-TB) has been enhanced by delays in the identification of resistant strains. However, resistance gene patterns and the extent and ...
Natural monocytic acquisition of haemozoin and rantes polymorphisms: association with malarial disease outcomes and functional changes in children from Wester...

Were, Tom (2011-08-15)

Plasmodium falciparum is an important cause of morbidity and mortality in children residing in holoendemic transmission areas largely from severe malarial anaemia (SMA). Although overproduction of inflammatory-derived ...
Non-Puerperal Uterine Inversion in a Young Woman: A Case Report, Brief Surgical Review, and Clinical Insights

Ouma, Kennedy O; Nelson, Brett D; Pinder, Leeya F (Clinical Medical Reviews and Case Reports, 2016-08)
A non-synonymous polymorphism in IL-23R Gene (rs1884444) is associated with reduced risk to schistosomiasis-associated Immune Reconstitution Inflammatory S...

Ogola, George O; Ouma, Collins; Jura, Walter G; Muok, Erick O; Colebunders, Robert; Mwinzi, Pauline N (BioMed Central, 2014-06-10)

Background Human Immunodeficiency Virus (HIV) and Schistosomiasis co-infection is common among residents at the shores of Lake Victoria in Kenya. About 36% of this population initiating antiretroviral therapy (ART) ...
Occupational Health and Safety Administration (OSHA) in the Morgues: Management and practice of the universal precautions in Morgues in Kenya

Okelloh, AM O; Onyango, R; Tonui, WK; Okumu, W; Ouma, C (2015)

: Morgues provide a risky work environment that requires universal safety precaution since it presents a variety of Occupational Health and Safety (OHS) challenges. Although OHS is a top priority internationally, in ...
Parasitemia, anemia, and malarial anemia in infants and young children in a rural holoendemic Plasmodium falciparum transmission area.

Were, T; Ong'echa, JM; Keller, CC; Ouma, C; Otieno, Richard O; Lewis, Z L; Ochie, D; Slingluff, JL; Mogere, S; Ogonji, GA; Orago, AS; Vulule, JM; Kaplan, SS; Day, RD; Perkins, DJ (American Journal of Tropical Medicine and Hygiene, 2005)

Malarial anemia (MA) is a multifactorial disease for which the complex etiological basis is only partially defined. The association of clinical, nutritional, demographic, and socioeconomic factors with parasitemia, ...
Polymorphic variability in the 3'untranslated region (UTR) of IL12B is associated with susceptibility to severe anaemia in Kenyan children with acute Plasmodium falc...

Ong'echa, John M; Raballah, Evans O; Kempaiah, Prakasha M; Anyona, Samuel B; Were, Tom; Davenport, Gregory C; Konah, Stephen; Vulule, John M; Ouma, Collins; Hittner, James B; Perkins, Douglas J (BioMed Central, 2011-08-06)

Plasmodium falciparum malaria remains a leading cause of morbidity and mortality among African children. Innate immunity provides the first line of defence against P. falciparum infections, particularly in young children ...
Polymorphic Variability in the 3'Untranslated Region (UTR) of IL12B is associated with Susceptibility to Severe Anaemia in Kenyan Children with Acute Plasmodium...

Raballah; Ong'echa, JM; Kempaiah, PM; Anyona, SB; Were, T; Davenport, GC; Konah, S; Vulule, JM; Ouma, C; Hittner, James B; Perkins, DJ (BioMed Central, 2005)

Plasmodium falciparum malaria remains a leading cause of morbidity and mortality among African children. Innate immunity provides the first line of defence against P. falciparum infections, particularly in young children ...
Polymorphic Variability in the Interleukin (IL)-1Beta Promoter Conditions Susceptibility to Severe Malarial Anemia and Functional Changes in IL-1Beta Production

Otieno, Micheal F; Ouma, C; Davenport, GC; Awandare, GA; Keller, CC; Were, T; Vulule, JM; Martinson, J; Ong'echa, JM; Ferrell, RE; Perkins, DJ (PubMed, 2012)

Interleukin (IL)-1beta is a cytokine released as part of the innate immune response to Plasmodium falciparum. Because the role played by IL-1beta polymorphic variability in conditioning the immunopathogenesis of severe ...
Polymorphisms in Fc gamma receptor (FcγRIIIA-176 F/V) and Toll-like receptor (TLR9 [-1237 T/C]) are associated with protection against severe malarial anemia an...

Munde, Elly O; Okeyo, Winnie A; Anyona, Samwel B; Raballah, Evans; Konah, Stephen; Okumu, Wilson; Ogonda, Lilian; Vulule, John; Ouma, Collins (American Society for Microbiology, 2012-10-08)

Understanding the immunogenetic basis of naturally acquired immunity to Plasmodium falciparum infection would aid in designing a rationally-based malaria vaccine. Variants within the Fc gamma receptors (FcγRs) mediate ...
Polymorphisms in the Fc gamma receptor IIIA and toll-like receptor 9 are associated with protection against severe malarial anemia and changes in circulating gam...

Munde, Elly O; Okeyo, Winnie A; Anyona, Samwel B; Raballah, Evans; Konah, Stephen; Okumu, Wilson; Ogonda, Lilian; Vulule, John; Ouma, Collins (American Society for Microbiology, 2012-12-01)

An understanding of the immunogenetic basis of naturally acquired immunity to Plasmodium falciparum infection would aid in the designing of a rationally based malaria vaccine. Variants within the Fc gamma receptors ...
Polymorphisms in the Fc Gamma Receptor IIIA and Toll-Like Receptor 9 Are Associated with Protection against Severe Malarial Anemia and Changes in Circulating...

Okeyo, Winnie; Anyona, Samwel; Raballah, Evan; Konah, Stephen; Ogoda, Lilian; Ouma, Collins (Journals. ASm. org, 2012-10-08)

An understanding of the immunogenetic basis of naturally acquired immunity to Plasmodium falciparum infection would aid in the designing of a rationally based malaria vaccine. Variants within the Fc gamma receptors ...

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