dc.description.abstract | The human immunodeficiency virus (HIV) pandemic presents ~ massive challenge to the
control of recurrent diseases like tuberculosis (TB) at all levels. Tuberculosis is also one of the
most common causes of morbidity and one of the leading causes of mortality in people living
with HIV/AIDS (PLWHA).
In this study, we have developed a mathematical model that captures the role played by
HIV/AIDS in accelerating the infection and hence spread of Tuberculosis. We looked at TB
progression among people with HIV and those without. The model is formulated for TBIHlV
negative individuals as well as for TBIHlV positive people. The model was developed using
the first order partial differential Mackendrick- Yon Foster equation.
Further, we reviewed different epidemiological techniques to estimate parameters in the model.
These parameters were estimated through extraction of relevant information from data
available in the literature. Finally, we were able to present computed numerical solutions of the
model using MATLAB. | en_US |