| dc.contributor.author | .Okwemba R. , Tarus P. K., Machocho A. K. , Wanyonyi A. W. , Waweru, I. M. , Onyancha J. M. , Onani M. O. and Amuka O. | |
| dc.date.accessioned | 2022-01-26T13:17:02Z | |
| dc.date.available | 2022-01-26T13:17:02Z | |
| dc.date.issued | 2018 | |
| dc.identifier.issn | :1996-0875 | |
| dc.identifier.uri | https://repository.maseno.ac.ke/handle/123456789/4663 | |
| dc.description | https://academicjournals.org/journal/JMPR/article-full-text-pdf/1D7639C56784.
Journal of Medicinal Plants Research | en_US |
| dc.description.abstract | A novel prenylfuroquinoline alkaloid capensenin (1), an alkaloid confusameline (2), two
furanocoumarins psolaren (3) and bergapten (4), were isolated from hexane and dichloromethane crude
extracts of stem bark, leaves and fruit pericarp of Calodendrum capense. Limonin (5) was also isolated
from the stem bark, while limonin diosphenol (6) was isolated from the seeds. Capensenin (1) showed
weak antimicrobial activity against Bacillus subtilis, while the leaves, stem bark and fruit pericarp crude
extracts exhibited activity against Staphylococcus aureus, B. subtilis and P. citrinum. Hexane pericarp
extract showed slight cytotoxicity to Vero cell E199 in 3-(4,5-dimethylthiazol-2-yl)-2,5-
diphenyltetrazolium bromide (MTT) assay. The structures of the compounds were elucidated by 1D and
2D nuclear magnetic resonance (NMR) spectroscopy, mass spectrometry and infra-red spectroscopy. | en_US |
| dc.subject | Capensenin, 4-hydroxyfuroquinoline, furanocoumarin, Calodendrum capense, alkaloid, Rutaceae | en_US |
| dc.title | Isolation, characterization and biological activity of organic extractives from Calodendrum capense (L.f.) Thunb.(Rutaceae) | en_US |
| dc.type | Article | en_US |
