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    Browsing by Author "Raballah, Evans"

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        (− 7402 T/G and-4729G/A) condition susceptibility to pediatric severe malarial anemia but not circulating IL-13 levels 

        Okumu, Wilson; Okeyo, Winnie A; Munde, Elly O; Raballah, Evans; Anyona, Samuel B; Vulule, John M; Ong’echa, John M; Perkins, Douglas J; Ouma, Collins (Bio Med Central, 2013)
        In holoendemic Plasmodium falciparum transmission areas such as western Kenya, severe malarial anemia [SMA, hemoglobin (Hb) < 6.0 g/dL, with any density parasitemia] is the most common clinical manifestation of severe ...
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        Association between Fcγ receptor IIA, IIIA and IIIB genetic polymorphisms and susceptibility to severe malaria anemia in children in western Kenya 

        Munde, Elly O; Okeyo, Winnie A; Raballah, Evans; Anyona, Samuel B; Were, Tom; Ong’echa, John M; Perkins, Douglas J; Ouma, Collins (BioMed Central, 2017-04-20)
        Background Naturally-acquired immunity to Plasmodium falciparum malaria develops after several episodes of infection. Fc gamma receptors (FcγRs) bind to immunoglobulin G (IgG) antibodies and mediate phagocytosis of ...
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        Communicating African spirituality through ecology: Challenges and prospects for the 21st century 

        Gumo, Sussy; Gisege, Simon O; Raballah, Evans; Ouma, Collins (2012-06-19)
        This review was set in the context of African spirituality and ecology. Specifically, the review addressed issues of African spirituality and the environment from a Kenyan context. Through analyses on existing literature, ...
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        Functional Haplotypes of Fc gamma (Fcγ) receptor (FcγRIIA and FcγRIIIB) predict risk to repeated episodes of severe malarial anemia and mortality in Kenyan children 

        Ouma, Collins; Davenport, Gregory C; Garcia, Steven; Kempaiah, Prakasha; Chaudhary, Ateefa; Were, Tom; Anyona, Samuel B; Raballah, Evans; Konah, Stephen N; Hittner, James B; Vulule, John M; Ong’echa, John M; Perkins, Douglas J (Springer-Verlag, 2012-02-01)
        Development of protective immunity against Plasmodium falciparum is partially mediated through binding of malaria-specific IgG to Fc gamma (γ) receptors. Variations in human FcγRIIA-H/R-131 and FcγRIIIB-NA1/NA2 affect ...
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        Haplotype of non-synonymous mutations within IL-23R is associated with susceptibility to severe malaria anemia in a P. falciparum holoendemic transmission area... 

        Munde, Elly O; Raballah, Evans; Okeyo, Winnie A; Ong’echa, John M; Perkins, Douglas J; Ouma, Collins (BioMed Central, 2017-04-20)
        Background Improved understanding of the molecular mechanisms involved in pediatric severe malarial anemia (SMA) pathogenesis is a crucial step in the design of novel therapeutics. Identification of host genetic ...
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        Interleukin (IL)-13 promoter polymorphisms (-7402 T/G and-4729G/A) condition susceptibility to pediatric severe malarial anemia but not circulating IL-13 levels 

        Okumu, Wilson; Okeyo, Winnie A; Munde, Elly O; Raballah, Evans; Anyona, Samuel B; Vulule, John M; Ong’echa, John M; Perkins, Douglas J; Ouma, Collins (BioMed Central, 2013-12)
        In holoendemic Plasmodium falciparum transmission areas such as western Kenya, severe malarial anemia [SMA, hemoglobin (Hb) < 6.0 g/dL, with any density parasitemia] is the most common clinical manifestation of severe ...
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        Knowledge and behaviour as determinants of anti-malarial drug use in a peri-urban population from malaria holoendemic region of western Kenya 

        Watsierah, Carren A; Jura, Walter G; Raballah, Evans; Kaseje, Dan; Abong'o, Benard; Ouma, Collins (BioMed Central, 2011-04-20)
        The appropriate use of anti-malarial drugs determines therapeutic efficacy and the emergence and spread of drug-resistant malaria. Strategies for improving drug compliance require accurate information about current ...
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        Polymorphisms in the Fc Gamma Receptor IIIA and Toll-Like Receptor 9 Are Associated with Protection against Severe Malarial Anemia and Changes in Circulating Gamma Interferon Levels 

        Munde, Elly O; Okeyo, Winnie A; Anyona, Samwel B; Raballah, Evans; Konah, Stephen; Okumu, Wilson; Ogonda, Lilian; Vulule, John; Ouma, Collins (American Society for Microbiology, 2012)
        An understanding of the immunogenetic basis of naturally acquired immunity to Plasmodium falciparum infection would aid in the designing of a rationally based malaria vaccine. Variants within the Fc gamma receptors (FcγRs) ...

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