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Hematological predictors of increased severe anemia in Kenyan children coinfected with Plasmodium falciparum and HIV‐1
(Wiley Subscription Services, Inc., A Wiley Company, 2010-04-01)
Malaria and HIV-1 are coendemic in many developing countries, with anemia being
the most common pediatric hematological manifestation of each disease. Anemia is also
one of the primary causes of mortality in children ...
Turning point
(Nature Research, 2011-02-01)
Collins Ouma became a molecular biologist to help thwart malaria's high mortality rate in his
native Kenya. Last November, he won the Royal Society Pfizer award for his work on
identifying genes that may confer protection ...
Functional Haplotypes of Fc Gamma (Fcy) Receptor (FcyRIIA and FcyRIIB) Predict Risk to Repeated Episodes of Severe Malarial Anaemia and Mortality in Kenyan...
(SN Konah, 2012)
Development of protective immunity against Plasmodium falciparum is partially mediated
through binding of malaria-specific IgG to Fc gamma (γ) receptors. Variations in human
FcγRIIA-H/R-131 and FcγRIIIB-NA1/NA2 affect ...
Functional promoter haplotypes of interleukin-18 condition susceptibility to severe malarial anemia and childhood mortality.
(PubMed, 2012)
Severe malarial anemia (SMA) is a leading cause of morbidity and mortality in children
residing in regions where plasmodium falciparum transmission is holoendemic. Although
largely unexplored in children with SMA, ...
Polymorphic Variability in the Interleukin (IL)-1Beta Promoter Conditions Susceptibility to Severe Malarial Anemia and Functional Changes in IL-1Beta Production
(PubMed, 2012)
Interleukin (IL)-1beta is a cytokine released as part of the innate immune response to
Plasmodium falciparum. Because the role played by IL-1beta polymorphic variability in
conditioning the immunopathogenesis of severe ...
Haplotypes of IL12B promoter polymorphisms condition susceptibility to severe malaria and functional changes in cytokine levels in Thai adults
(Immunogenetics, 2012)
Polymorphic variability in immune response genes, such as IL12B, encoding the IL-12p40
subunit is associated with susceptibility to severe malaria in African populations. Since the
role of genetic variation in conditioning ...
MIF (macrophage migration inhibitory factor) promoter polymorphisms and susceptibility to severe malarial anemia
(Journal of Infectious Diseases, 2012)
Severe malarial anemia (SMA) resulting from Plasmodium falciparum
infection is one of the leading causes of childhood mortality in sub-Saharan Africa. The
innate immune mediator macrophage migration inhibitory factor ...
Assessment of palliative care services in western Kenya
(AME, 2017-01)
Background: The need for palliative care services is rapidly increasing due to the rising number of patients with non-communicable diseases. The objective of this study was to assess the current availability and barriers ...
Non-Puerperal Uterine Inversion in a Young Woman: A Case Report, Brief Surgical Review, and Clinical Insights
(Clinical Medical Reviews and Case Reports, 2016-08)
Development of a Unifying Target and Consensus Indicators for Global Surgical Systems Strengthening: Proposed by the Global Alliance for Surgery, Obstetric, Trauma, and …
(SPRINGER, 2017-10-01)
After decades on the margins of primary health care, surgical and anaesthesia care is
gaining increasing priority within the global development arena. The 2015 publications of
the Disease Control Priorities third edition ...