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Costs of continuing RTS, S/ASO1E malaria vaccination in the three malaria vaccine pilot implementation countries
(Public Library of Science, 2021-01-11)
The RTS,S/ASO1E malaria vaccine is being piloted in three countries—Ghana, Kenya, and Malawi—as part of a coordinated evaluation led by the World Health Organization, with support from global partners. This study estimates ...
Correction: Costs of continuing RTS, S/ASO1E malaria vaccination in the three malaria vaccine pilot implementation countries
(Public Library of Science, 2021-04-22)
Cost estimates under additional vaccine price assumptions are not included in the main result Table (Table 3). Please view S4 Table,“Unit cost of continuing to vaccinate in pilot areas at various vaccine prices,” for results ...
National stakeholder preferences for next-generation rotavirus vaccines: Results from a six-country study
(Elsevier, 2022-01-21)
Currently available live, oral rotavirus vaccines (LORVs) have significantly reduced severe rotavirus hospitalizations and deaths worldwide. However, LORVs are not as effective in low- and middle-income countries (LMIC) ...
Healthcare provider perspectives on delivering next generation rotavirus vaccines in five low-to-middle-income countries
(Public Library of Science, 2022-06-23)
Live oral rotavirus vaccines (LORVs) have significantly reduced rotavirus hospitalizations and deaths worldwide. However, LORVs are less effective in low- and middle-income countries (LMICs). Next-generation rotavirus ...
Genetic variation in CSF2 (5q31.1) is associated with longitudinal susceptibility to pediatric malaria, severe malarial anemia, and all-cause mortality in a high-burden malaria and HIV region of Kenya
(BioMed Central, 2022)
Plasmodium falciparum infections remain among the leading causes of morbidity and mortality in holoendemic transmission areas. Located within region 5q31.1, the colony-stimulating factor 2 gene (CSF2) encodes granulocyte ...
Impact of integrated water, sanitation, hygiene, health and nutritional interventions on diarrhoea disease epidemiology and microbial quality of water in a resource-constrained setting in Kenya: A controlled intervention study
(Wiley online library, 2022)
We assessed the impact of water, hygiene and sanitation (WASH), maternal,new-born and child health (MNCH), nutrition and early childhood development (ECD) on diarrhoea and microbial quality of water in a resource-constrained ...
Genetic differentiation in East African ethnicities and its relationship with endurance running success
(Public Library of Science, 2022)
Since the 1960s, East African athletes, mainly from Kenya and Ethiopia, have dominated long-distance running events in both the male and female categories. Further demographic studies have shown that two ethnic groups are ...
Nonsynonymous amino acid changes in the α-chain of complement component 5 influence longitudinal susceptibility to Plasmodium falciparum infections and severe malarial anemia in kenyan children
(Frontiers, 2022)
Severe malarial anemia (SMA; Hb < 5.0 g/dl) is a leading cause of childhood morbidity and mortality in holoendemic Plasmodium falciparum transmission regions such as western Kenya.
The prevalence and management strategies of gestational urinary tract infections (UTI) in Kisumu County, Kenya
(Cold Spring Harbor Laboratory Press, 2022)
Urinary tract infections (UTI) contribute to substantive proportions of adverse pregnancy outcomes. Current national statistics in Kenya show high maternal mortality (488/100,000) and neonatal mortality (24/1,000) rates. ...
Evidence of co-exposure with Brucella spp, Coxiella burnetii, and Rift Valley fever virus among various species of wildlife in Kenya
(Public Library of Science, 2022-09)
Co-infection, especially with pathogens of dissimilar genetic makeup, may result in a more
devastating impact on the host. Investigations on co-infection with neglected zoonotic pathogens in wildlife are necessary to ...