Browsing Biomedical Science by Issue Date
Now showing items 21-40 of 40
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The diagnostic accuracy, sensitivity and specificity of fine needle aspiration cytology in evaluating thyroid masses at Moi teaching and referral hospital
(2016)Thyroid masses are common surgical presentations with a worldwide prevalence of 4–7% in the general adult population. Africa, specifically Kenya is not excluded from these surgical conditions. The vast majority of adult ... -
Antibody Responses to Plasmodium Falciparum Antigens in Hiv Infected Adults in Bondo Sub County Hospital, Siaya County, Kenya
(Maseno University, 2016)Malaria and human immunodeficiency virus (HIV) are co-endemic in sub-Saharan Africa. Infection with HIV results in B cell anomalies. Antibodies are critical in protection against malaria and it is hypothesized that B cell ... -
Development of antibody dependent respiratory burst assay as a tool for evaluating cellular immunity to malaria
(Maseno University, 2016)Malaria vaccine clinical trials in exposed populations have not always been consistent in finding robust associations between the predicted immune responses and protection against disease. The selection of most promising ... -
Characterization and source tracking of diarrheagenic bacteria contaminating fish in lake victoria, Kenya
(Maseno University, 2016)Lake Victoria is an important source of fish. Nonetheless, fish has been reported to be of low microbiological quality as they have been reported to be contaminated with Escherichia coli, Vibrio spp, Shigella spp and ... -
Comparison of diagnostic performance of mini-flotac with formalin-ether concentration and kato-katz for detection of intestinal helminths and protozoa in nursery school children in Mbita, Western Kenya
(Maseno University, 2016)Schistosoma mansoni (S. mansoni), soil-transmitted helminths (STH) and protozoa affect approximately 2 billion people world-wide. Most of these infections occur in developing countries and children below 14 years of age ... -
Influence of cyp2b6 polymorphisms on cd4+ t cell count and HIV RNA viral load changes among individuals on nevirapine Containing highly active antiretroviral therapy
(Maseno University, 2016)Human Immunodeficiency Virus (HIV) remains the leading cause of morbidity and mortality in Kenya with a prevalence of 6.5%. Highly active antiretroviral therapy (HAART) is used to manage the disease by increasing the CD4 ... -
Antimicrobial Activities of Secondary Metabolites From Vernonia Adoensis and Ocimum Kilimandscharicum Medicinal Plants and Associated Endophytes From Kakamega Forest in Kenya
(Maseno University, 2016)Medicinal plants have been used for the treatment of different ailments in human and animal health systems for many years. Approximately over 80% of rural and urban African populations use plant-based synthetic products ... -
Effect of knockdown resistance on plasmodium falciparum sporozoite rates in malaria vectors in western Kenya
(Maseno University, 2017) -
Isoniazid and Rifampicin Resistance and Patient Treatment Response in a Tuberculosis and Hiv-1 Co-Endemic Population in Western Kenya in 2012-2014
(Maseno University, 2017)In 2015, 10.4 million people worldwide had tuberculosis (TB) and 1.4 million deaths occurred, 400 000 of whom were HIV-positive, Sub-Saharan Africa (SSA) accounted for 81% of these cases. In 2015, 480 000 new cases of ... -
Phenotypic characterization of virulence, evolutionary Relationship and global expansion in Trypanosoma evansi isolates from Surra endemic regions
(Maseno University, 2018)ABSTRACT Trypanosoma evansi parasite is the causative agent of trypanosomiasis (surra) in camels and other livestock with devastating economic consequences in many parts of the world, including Kenya, Vietnam, Brazil, ... -
Evaluation of the performance of Sacace HPV genotypes 14 real-tm quant and Carehpv against linear array in detection of human Papilloma virus genotypes in women from Western Kenya
(Maseno University, 2018)Cervical cancer (CC) is common among women, with global estimates of over 530,000 new cases and over 270,000 deaths annually. Human papilloma virus (HPV) infection increases the risk for CC development while high HIV ... -
Clinical equivalence of heparinized arterial plasma to venous Serum for magnesium and phosphate measurement among Patients admitted at the intensive care unit of Moi teaching and referral hospital
(Maseno University, 2018)Electrolytes routinely measured in patients in Intensive Care Unit (ICU) are sodium, potassium, chloride, calcium, magnesium and phosphate. Of these; sodium, potassium, chloride and calcium are measured as part of tests ... -
Efficacy of Chlorfenapyr and Clothianidin Insecticides on Anopheles Malaria Vector populations of Nyando, Bumula and Ndhiwa sub-counties, Western Kenya
(Maseno University, 2018)Malaria is a global health problem resulting in 435,000 deaths annually with 90% of the deaths occurring in sub-Saharan Africa. Over 70% of the Kenyan population is at risk of malaria and western Kenya is an endemic region ... -
Association between genetic variations in selected cell receptors and nuclear transcription factors and susceptibility to Paediatric p. Falciparum severe malaria Anaemia in Siaya county, Western Kenya
(Maseno University, 2018)ABSTRACT Plasmodium falciparum severe malaria aneamia [SMA, haemoglobin (Hb) <5.0 g/dL or Hb<6.0 g/dL with any parasite density] remains the most life-threatening malaria. With its immuno-genetic basis partially understood, ... -
Association between Ifn-γ, Tnf-α, Fcγriia and il-12β gene Polymorphisms and Susceptibility to Endemic Burkitt Lymphoma in children from Western Kenya
(Maseno University, 2018)Endemic Burkitt lymphoma (eBL) is an aggressive paediatric B-cell lymphoma prevalent in children from holoendemic malaria regions of sub-Saharan Africa. It is associated with early primary Epstein-Barr virus (EBV) and ... -
Prevalence and intensity of the common Parasitic infections and Anaemia in street children compaired to school going children in Kisumu city, Kenya.
(Maseno University, 2018)The provision of skilled care during delivery is an indicator to monitor progress in reducing maternal mortality and falls in Goal 3 of the Sustainable Development Goals (SDGs). However, the proportion of Skilled Birth ... -
Polymorphisms of toll like receptor 4 (-8984c/g and 299asp/gly) and Interferon gamma levels in children with severe Plasmodium Falciparum malaria Anaemia in Siaya county, Western Kenya
(Maseno University, 2018)Plasmodium falciparum (P. falciparum) malaria is a major cause of childhood morbidity and mortality in Sub-Saharan Africa despite the integrated approaches put in place to control the disease. Most of the mortality in ... -
Temporal and spatial trends of plasmodium falciparum multi-drug resistance protein 1 gene mutations during implementation of artemisinin combination therapies between 2008 and 2019 in Kenya
(Maseno university, 2021)Single nucleotide polymorphisms (SNPs) in the Plasmodium falciparum multi-drug resistance protein 1 (Pfmrp1) gene have previously been associated with conferring resistance against artemisinin and its partner drugs in ... -
Profile of drug resistance conferring gene mutations in Mycobacterium tuberculosis among new and previously treated pulmonary tuberculosis cases from Kisumu county, Kenya
(Maseno University, 2023)Tuberculosis (TB) remains a significant public health concern in Kisumu County, Kenya, with a high burden of drug-resistant cases. Existing studies focus on epidemiological aspects, but lack comprehensive investigation ...