Browsing Department of Biomedical Sciences by Issue Date
Now showing items 21-40 of 81
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Antimalarials: Review of Plasmepsins as Drug Targets and HIV Protease Inhibitors Interactions
(Bentham Science Publishers, 2018)Malaria is a major global health concern with the majority of cases reported in regions of South-East Asia, Eastern Mediterranean, Western Pacific, the Americas, and Sub-Saharan Africa. The World Health Organization (WHO) ... -
Low Levels of Human Antibodies to Gametocyte-Infected Erythrocytes Contrasts the PfEMP1-Dominant Response to Asexual Stages in P. falciparum Malaria
(Frontier in Immunology, 2018)Vaccines that target Plasmodium falciparum gametocytes have the potential to reduce malaria transmission and are thus attractive targets for malaria control. However, very little is known about human immune responses to ... -
Status of aflatoxin contamination in cow milk produced in smallholder dairy farms in urban and peri-urban areas of Nairobi County: a case study of Kasarani sub county, Kenya
(Taylor & Francis, 2018)Introduction: Milk consumption in Kenya supersedes other countries in East Africa. However, milk contamination with aflatoxin M1 (AFM1) is common, but the magnitude of this exposure and the health risks are poorly ... -
Young Adults in Endemic Areas: An Untreated Group in Need of School-Based Preventive Chemotherapy for Schistosomiasis Control and Elimination
(Tropical Medicine and Infectious Disease, 2018)Parasitologic surveys of young adults in college and university settings are not commonly done, even in areas known to be endemic for schistosomiasis and soil-transmitted helminths. We have done a survey of 291 students ... -
Assessment of Organizational Factors for Health Management Information System (HMIS) Performance in Elgeiyo Marakwet County, Kenya.
(EPH - International Journal of Medical and Health Science, 2018-03)Health Management Information Systems (HMIS) have been used by many countries using platforms adopted or own-designed. It’s implemented by integrating all healthcare services and gives service providers the ability to ... -
Impact of Four Years of Annual Mass Drug Administration on Prevalence and Intensity of Schistosomiasis among Primary and High School Children in Western Kenya: A Repeated Cross-Sectional Study.
(The American journal of tropical medicine and hygiene, 2018-03-12)Schistosomiasis remains a major public health problem in Kenya. The World Health Organization recommends preventive chemotherapy with praziquantel (PZQ) to control morbidity due to schistosomiasis. Morbidity is considered ... -
Seroprevalence and determinants of transfusion transmissible infections among voluntary blood donors in Homabay, Kisumu and Siaya counties in western Kenya
(BioMed Central, 2018-03-12)Since the implementation of a series of blood donation safety improvements in Kenya, information about seroprevalence and determinants of transfusion transmissible infections among voluntary blood donors especially in high ... -
Reactive case detection of Plasmodium falciparum in western Kenya highlands: effective in identifying additional cases, yet limited effect on transmission
(BioMed Central, 2018-03-13)Background: Identifying asymptomatic reservoirs of malaria parasites using index cases as entry points into the community is potentially a cost-efective way towards achieving malaria elimination. Methods: Within 1 year, ... -
Barriers and Opportunities to Advancing Women in Leadership Roles in Vector Control: Perspectives from a Stakeholder Survey
(The American journal of tropical medicine and hygiene, 2018-03-19)Increasing the active participation of professional women in vector control (VC) activities may help promote greater gender equity in the workplace and reduce the burden of vector-borne diseases. This stakeholder survey ... -
CRITICAL FACTORS AND CREDIT UPTAKE IN YOUTH ENTERPRISE DEVELOPMENT FUND IN SUNA EAST CONSTITUENCY, MIGORI COUNTY, KENYA
(KENYATTA UNIVERSITY, 2018-11)Youth entrepreneurship in Kenya plays a significant role in enhancing Kenya’s economic development and in reducing youth unemployment. Despite the great significance of entrepreneurship in Kenya, there is a high failure ... -
CRITICAL FACTORS AND CREDIT UPTAKE IN YOUTH ENTERPRISE DEVELOPMENT FUND IN SUNA EAST CONSTITUENCY, MIGORI COUNTY, KENYA
(KENYATTA UNIVERSITY, 2018-11)Youth entrepreneurship in Kenya plays a significant role in enhancing Kenya’s economic development and in reducing youth unemployment. Despite the great significance of entrepreneurship in Kenya, there is a high failure ... -
Enzymatic Activity of Endophytic Bacterial Isolates from Selected Mangrove Plants in Kenya
(The Open Microbiology Journal, 2018-11-14)Microorganisms are a preferred source of enzyme production due to their high production capability and low cost of production. Bacterial endophytes occupy unexplored sites hence they represent a new source of enzymes with ... -
Safe Anesthesia Care in Western Kenya: A Preliminary Assessment of the Impact of Nurse Anesthetists at Multiple Levels of Government Hospitals
(International Anesthesia Research, 2019)BACKGROUND: Only 20% of the surgical burden in eastern sub-Saharan Africa is currently met, leaving >17 million surgical cases annually in need of safe surgery and anesthesia. Similarly, there is an extreme shortage of ... -
Metabollic syndrome components as a risk factor to the health status of university students in Kenya
(IJCIRAS, 2019)An efficient healthcare system targets the maintenance or improving the health position for citizens that can be achieved through disease and illness prevention based on curative and preventive care. Kenya currently ... -
Investigating treatment response of patients with confirmed drug-resistant tuberculosis in an hiv-1-endemic population in western Kenya
(BMJ, 2019)In 2015, 10.4 million people worldwide had tuberculosis (TB) and 1.4 million deaths occurred, 400 000 of whom were HIV-positive. Sub-Saharan Africa accounted for 81% of these cases. In western Kenya, current data on the ... -
16S rRNA gene profiling of bacterial communities mediating production of tsetse attractive phenols in mammalian urine
(AOSIS Publishing, 2019)Several types of odours are involved in the location of host animals by tsetse (Diptera: Glossinidae), a vector of animal African trypanosomiasis. Host animals' ageing urine has been shown to be the source of a phenolic ... -
Sensitive detection of EBV microRNAs across cancer spectrum reveals association with decreased survival in adult acute myelocytic leukemia
(Scientific Report, 2019)Epstein Barr virus (EBV) is the etiologic agent involved in numerous human cancers. After infecting the host, EBV establishes a latent infection, with low levels of messenger RNA (mRNA) and protein expression, evolved ... -
The diagnostic accuracy of Th1 (IFN-γ, TNF-α, and IL-2) and Th2 (IL-4, IL-6 and IL-10) cytokines response in AFB microscopy smear negative PTB- HIV co-infected patients
(Springer, 2019)Acid Fast Bacilli (AFB) microscopy smear remains the most widely used laboratory diagnostic technique for Pulmonary Tuberculosis (PTB) in low-and-middle income countries. Although it is highly specifc, the sensitivity ... -
Molecular basis of reduced LAIR1 expression in childhood severe malarial anaemia: Implications for leukocyte inhibitory signalling
(science direct, 2019)Leukocyte-associated immunoglobulin like receptor-1 (LAIR1) is a transmembrane inhibitory receptor that influences susceptibility to a myriad of inflammatory diseases. Our recent investigations of severe malarial anaemia ... -
Impact of processing methods on microbial load of reared and wild-caught edible crickets (Scapsipedus icipe and Gryllus bimaculatus) in Kenya
(Wageningen Academic Publishers, 2019-07-10)The microbial composition of farmed and wild Scapsipedus icipe and Gryllus bimaculatus is presented. The aim of this study is to determine the microbial load of the two cricket species and evaluate the efficiency of ...