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Intermittent screening and treatment or intermittent preventive treatment with dihydroartemisinin–piperaquine versus intermittent preventive treatment with sulfadoxine …
(Elsevier, 2015)
Background
Every year, more than 32 million pregnancies in sub-Saharan Africa are at risk of malaria infection and its adverse consequences. The effectiveness of the intermittent preventive treatment with sulfadoxine–py ...
Intermittent preventive treatment of malaria in pregnancy with mefloquine in HIV-infected women receiving cotrimoxazole prophylaxis: a multicenter randomized placebo-controlled
(Public Library of Science, 2014)
Background: Intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) is recommended
for malaria prevention in HIV-negative pregnant women, but it is contraindicated in HIV-infected women ...
Barriers and facilitators to antenatal and delivery care in western Kenya: a qualitative study
(BioMed Central, 2015)
Background
In western Kenya, maternal mortality is a major public health problem estimated at 730/100,000 live births, higher than the Kenyan national average of 488/100,000 women. Many women do not attend antenatal care ...
Effect of malaria rapid diagnostic tests on the management of uncomplicated malaria with artemether-lumefantrine in Kenya: a cluster randomized trial
(The American Society of Tropical Medicine and Hygiene, 2009)
Shortly after Kenya introduced artemether-lumefantrine (AL) for first-line treatment of uncomplicated
malaria, we conducted a pre-post cluster randomized controlled trial to assess the effect of providing malaria rapid ...
Antifolate Resistance in Plasmodium falciparum: Multiple Origins and Identification of Novel dhfr Alleles
(The University of Chicago Press, 2006)
BackgroundSulfadoxine-pyrimethamine has been widely used as first-line therapy for uncomplicated malaria throughout sub-Saharan Africa. Recent studies conducted in Asia and Africa suggest the triple-mutant dhfr genotype ...
An analysis of pregnancy-related mortality in the KEMRI/CDC health and demographic surveillance system in western Kenya
(Public Library of Science, 2013)
Background: Pregnancy-related (PR) deaths are often a result of direct obstetric complications occurring at childbirth.
Methods and Findings: To estimate the burden of and characterize risk factors for PR mortality, we ...
Effectiveness of antenatal clinics to deliver intermittent preventive treatment and insecticide treated nets for the control of malaria in pregnancy in Kenya
(Public Library of Science, 2013)
Background: Malaria in pregnancy can have devastating consequences for mother and baby. Coverage with the WHO
prevention strategy for sub-Saharan Africa of intermittent-preventive-treatment (IPTp) with two doses of ...
Does cotrimoxazole prophylaxis for the prevention of HIV-associated opportunistic infections select for resistant pathogens in Kenyan adults?
(The American Society of Tropical Medicine and Hygiene, 2008)
We assessed the effect of daily cotrimoxazole, essential for HIV care, on development of antifolateresistant Plasmodium falciparum, naso-pharyngeal Streptococcus pneumoniae (pneumococcus), and commensal Escherichia coli. ...
Antenatal and delivery care in rural western Kenya: the effect of training health care workers to provide" focused antenatal care"
(BioMed Central, 2010)
Background
Maternal mortality remains high in developing countries and data to monitor indicators of progress in maternal care is needed. We examined the status of maternal care before and after health care worker (HCW) ...
Malaria and anaemia among pregnant women at first antenatal clinic visit in Kisumu, western Kenya
(Blackwell Publishing Ltd, 2007)
objective To determine the prevalence of malaria and anaemia among urban and peri-urban women
attending their first antenatal clinic (ANC) in an area of perennial malaria transmission.
methods Between November 2003 and ...