Browsing School of Medicine by Title

Now showing items 481-500 of 553

    • Safety and Acceptability of Thermal Ablation for Treatment of Human Papillomavirus Among Women Living With HIV in Western Kenya 

      Chemtai Mungo, Cirilus Ogollah Osongo, Jeniffer Ambaka, Magdalene A Randa, Jackton Omoto, Craig R Cohen, Megan Huchko (American Society of Clinical Oncology, 2020-07)
      PURPOSE The WHO now recommends thermal ablation as an alternative to cryotherapy within “screen-and-treat” cervical cancer programs in low- and middle-income countries (LMICs). We conducted a safety and acceptability ...

    • Safety and immunogenicity of RTS, S/AS01 malaria vaccine in infants and children with WHO stage 1 or 2 HIV disease: a randomised, double-blind, controlled trial 

      Lucas Otieno, Martina Oneko, Walter Otieno, Joseph Abuodha, Emmanuel Owino, Chris Odero, Yolanda Guerra Mendoza, Ben Andagalu, Norbert Awino, Karen Ivinson, Dirk Heerwegh, Nekoye Otsyula, Maria Oziemkowska, Effua Abigail Usuf, Allan Otieno, Kephas Otieno, Didier Leboulleux, Amanda Leach, Janet Oyieko, Laurence Slutsker, Marc Lievens, Jessica Cowden, Didier Lapierre, Simon Kariuki, Bernhards Ogutu, Johan Vekemans, Mary J Hamel (Elsevier, 2016)
      Background Malaria remains a major global public health concern, especially in sub-Saharan Africa. The RTS,S/AS01 malaria candidate vaccine was reviewed by the European Medicines Agency and received a positive scientific ...

    • Safety and immunogenicity of the RTS, S/AS01 malaria vaccine in infants and children identified as HIV-infected during a randomized trial in sub-Saharan Africa 

      Lucas Otieno, Yolanda Guerra Mendoza, Samuel Adjei, Tsiri Agbenyega, Selidji Todagbe Agnandji, Pedro Aide, Pauline Akoo, Daniel Ansong, Kwaku Poku Asante, James A Berkley, Samwel Gesase, Mary J Hamel, Irving Hoffman, Seyram Kaali, Portia Kamthunzi, Simon Kariuki, Peter Kremsner, Miguel Lanaspa, Bertrand Lell, Marc Lievens, John Lusingu, Anangisye Malabeja, Nahya Salim Masoud, Ali Takadir Mtoro, Patricia Njuguna, Opokua Ofori-Anyinam, Godfrey Allan Otieno, Walter Otieno, Seth Owusu-Agyei, Lode Schuerman, Hermann Sorgho, Marcel Tanner, Halidou Tinto, Innocent Valea, Pascale Vandoolaeghe, Jahit Sacarlal, Martina Oneko (Vaccine, 2020)
      We assessed the safety and immunogenicity of the RTS,S/AS01 malaria vaccine in a subset of children identified as HIV-infected during a large phase III randomized controlled trial conducted in seven sub-Saharan African ...

    • Safety and immunogenicity of the RTS, S/AS01 malaria vaccine in infants and children identified as HIV-infected during a randomized trial in sub-Saharan Africa 

      Lucas Otieno, Yolanda Guerra Mendoza, Samuel Adjei, Tsiri Agbenyega, Selidji Todagbe Agnandji, Pedro Aide, Pauline Akoo, Daniel Ansong, Kwaku Poku Asante, James A Berkley, Samwel Gesase, Mary J Hamel, Irving Hoffman, Seyram Kaali, Portia Kamthunzi, Simon Kariuki, Peter Kremsner, Miguel Lanaspa, Bertrand Lell, Marc Lievens, John Lusingu, Anangisye Malabeja, Nahya Salim Masoud, Ali Takadir Mtoro, Patricia Njuguna, Opokua Ofori-Anyinam, Godfrey Allan Otieno, Walter Otieno, Seth Owusu-Agyei, Lode Schuerman, Hermann Sorgho, Marcel Tanner, Halidou Tinto, Innocent Valea, Pascale Vandoolaeghe, Jahit Sacarlal, Martina Oneko (Elsevier, 2020-01-22)
      We assessed the safety and immunogenicity of the RTS,S/AS01 malaria vaccine in a subset of children identified as HIV-infected during a large phase III randomized controlled trial conducted in seven sub-Saharan African ...

    • Safety profile of the RTS, S/AS01 malaria vaccine in infants and children: additional data from a phase III randomized controlled trial in sub-Saharan Africa 

      Yolanda Guerra Mendoza, Elodie Garric, Amanda Leach, Marc Lievens, Opokua Ofori-Anyinam, Jean-Yves Pirçon, Jens-Ulrich Stegmann, Pascale Vandoolaeghe, Lucas Otieno, Walter Otieno, Seth Owusu-Agyei, Jahit Sacarlal, Nahya Salim Masoud, Hermann Sorgho, Marcel Tanner, Halidou Tinto, Innocent Valea, Ali Takadir Mtoro, Patricia Njuguna, Martina Oneko, Godfrey Allan Otieno, Kephas Otieno, Samwel Gesase, Mary J Hamel, Irving Hoffman, Seyram Kaali, Portia Kamthunzi, Peter Kremsner, Miguel Lanaspa, Bertrand Lell, John Lusingu, Anangisye Malabeja, Pedro Aide, Pauline Akoo, Daniel Ansong, Kwaku Poku Asante, James A Berkley, Samuel Adjei, Tsiri Agbenyega, Selidji Todagbe Agnandji, Lode Schuerman (Taylor & Francis, 2019-10-03)
      A phase III, double-blind, randomized, controlled trial (NCT00866619) in sub-Saharan Africa showed RTS, S/AS01 vaccine efficacy against malaria. We now present in-depth safety results from this study. 8922 children ...

    • Safety profile of the RTS,S/AS01 malaria vaccine in infants and children: additional data from a phase III randomized controlled trial in sub-Saharan Africa 

      Yolanda Guerra Mendoza, Elodie Garric, Amanda Leach, Marc Lievens, Opokua Ofori-Anyinam, Jean-Yves Pirçon, Jens-Ulrich Stegmann, Pascale Vandoolaeghe, Lucas Otieno, Walter Otieno, Seth Owusu-Agyei, Jahit Sacarlal, Nahya Salim Masoud, Hermann Sorgho, Marcel Tanner, Halidou Tinto, Innocent Valea, Ali Takadir Mtoro, Patricia Njuguna, Martina Oneko, Godfrey Allan Otieno, Kephas Otieno, Samwel Gesase, Mary J Hamel, Irving Hoffman, Seyram Kaali, Portia Kamthunzi, Peter Kremsner, Miguel Lanaspa, Bertrand Lell, John Lusingu, Anangisye Malabeja, Pedro Aide, Pauline Akoo, Daniel Ansong, Kwaku Poku Asante, James A Berkley, Samuel Adjei, Tsiri Agbenyega, Selidji Todagbe Agnandji, Lode Schuerman (Taylor & Francis, 2019)
      A phase III, double-blind, randomized, controlled trial (NCT00866619) in sub-Saharan Africa showed RTS,S/AS01 vaccine efficacy against malaria. We now present in-depth safety results from this study. 8922 children (enrolled ...

    • Same day colposcopic examination and loop electrosurgical excision procedure (LEEP) presents minimal overtreatment and averts delay in treatment of cervical intraepithelial … 

      Kays Muruka, Mugo R Nelly, Wanyoike Gichuhi, Kihara Anne-Beatrice, Cheserem J Eunice, Kosgei J Rose (Scientific Research Publishing, 2013-05-08)
      Background: Screening for cancer of the cervix at Kenyatta National Hospital (KNH), follows the recommended three-step strategy; Papanicolaou (Pap) smear, colposcopy/biopsy and loop electrosurgical excision procedure ...

    • Screening of Bioactive Secondary Metabolites from Sea Sponge (Clathria Indica) Against Bacteria Associated with Urinary Tract Infections 

      GO Mauti EM Mauti GA Ouno FL Shamala (Journal of the Open University of Tanzania, 2013)
      The marine sponge Clathria indica, collected from Thondi-Palk Strait region of Tamil Nadu, was studied for bacterial antagonistic activity. Sponge species were identified based on specula morphology. Ethyl Acetate extracts ...

    • Sehistosoma Mansoni in the Baboon: Modulation of Pathology After Vaccination with Polyclonal Anti‐Idiotypic Antibodies 

      Borus, Pk; Nyindo, M; Farah, IO; Oguya, FO; Makawiti, Dominic W (Blackwell Publishing Ltd, 1995-12-01)
      Vaccination of five baboons with an anti-idiotypic vaccine to irradiated Schistosoma mansoni cercariae resulted in nearly 19% protection compared to 39% protection conferred to five baboons vaccinated with an irradiated ...

    • Selected genes of Human herpesvirus-8 associated Kaposi’s sarcoma among patients with Human Immunodeficiency Virus-1 and Acquired Immunodeficiency Disease Syndrome 

      Demba, Rodgers Norman, Nathan Shaviya, Sylviah Mweyeli Aradi, Walter Mwanda (AJOL, 2019)
      Kaposi's sarcoma (KS) is a kind of cancer that causes flat or raised lesions containing Human herpes virus 8 (HHV8). The KS lesions are common among immunosuppressed HIV patients. Highly Active Antiretroviral (HHART) treats ...

    • Selective Blockade of Trypanosomatid Protein Synthesis by a Recombinant Antibody Anti-Trypanosoma cruzi P2β Protein 

      Ayub, Maximiliano J; Nyambega, Benson; Simonetti, Leandro; Duffy, Tomas; Longhi, Silvia A; Gómez, Karina A; Hoebeke, Johan; Levin, Mariano J; Smulski, Cristian R (Public Library of Science, 2012-05-03)
      The ribosomal P proteins are located on the stalk of the ribosomal large subunit and play a critical role during the elongation step of protein synthesis. The single chain recombinant antibody C5 (scFv C5) directed against ...

    • Sensitivity of 3D7 and W2 Clones in a Formulated Transport Medium and EDTA Anticoagulants against a Panel of Antimalarials 

      Scolastica C. Korir1 Rose M. Kakai1 Hosea M. Akala2 (Journal of Biology, Agriculture and Healthcare, 2016)
      Introduction: in vitro drug sensitivity relies on the growth of plasmodium in the presence of the antimalarials. These fresh isolates brought in for assay from collection sites normally not near the laboratory require a ...

    • SEROPREVALENCE OF CHLAMYDOPHILA PSITTACIAMONG EMPLOYEES OF TWO GERMAN DUCK FARMS 

      Raimond Lugert, Uwe Groß, Wycliffe O Masanta, Gunter Linsel, Astrid Heutelbeck, Andreas E Zautner (Akadémiai Kiadó, 2017)
      Psittacosis is a zoonotic infectious disease that is caused by Chlamydophila psittaci. To determine the occupational risk of getting the infection, we investigated the seroprevalence of C. psittaci among employees of two ...

    • Seroprevalence of hepatitis B surface antigen and it’s associated factors among hiv positive pregnant women in Jaramogi Oginga Odinga Teaching and Referral 

      Joseph N Ngerecia (University of Nairobi, 2015)
      Introduction: Hepatitis B Virus (HBV) and Human Immunodeficiency Virus (HIV) are among the leading causes of infectious disease deaths worldwide. The two viruses are highly endemic in sub-Saharan Africa. Pregnant women who ...

    • Serum cystatin C for assessment of glomerular filtration rate in hypertensive disorders of pregnancy 

      J Moodley, R Gangaram, R Khanyile, PJ Ojwang (Taylor & Francis, 2004-01-01)
      Assessment of renal function is important in the evaluation of the pregnant hypertensive patient. The aim of this study was to evaluate the diagnostic utility of cystatin C as a marker of glomerular filtration rate in ...

    • Seven key actions to eradicate rheumatic heart disease in Africa: the Addis Ababa communiqué: cardiovascular topics 

      Mohammed Al-Kebsi, Azza Abul-Fadl, Mark Engel, Ana Olga Mocumbi, Steve Justus, Gasnat Shaboodien, Bernard Gitura, Alaa Elghamrawy, Joris Van Dam, Abraha Hailu, Liesl Zuhlke, Dike Ojji, George Nel, Elijah Ogola, Diana Lennon, John Musuku, Pindile Mntla, Abiodun Adeoye, Christopher Hugo-Hamman, David Watkins, Albertino Damasceno, Louis Murango, Charles Mondo, Mabvuto Kango, Ganesan Karthikeyan, Jonathan Carapetis, Stephen Ogendo, Mahmoud Sani, Steven Shongwe, Agnes Mtaja, Kamanzi Emmanuel Rusingiza, Fidelia Bode-Thomas, Yoseph Mamo, Sahar Sheta, Mekia Mohammed Redi, Rezeen Daniels, Bongani M Mayosi, Gene Bukhman, Joseph Mucumbitsi, Veronica Francis, Sulafa Ali, Habib Gamra, Abraham Haileamlak, Peter Lwabi, Chris Sutton, Taiwo Olabisi Olunuga, Neil Kennedy, Dejuma Yadeta Goshu (Sabinet, 2016-05-01)
      Acute rheumatic fever (ARF) and rheumatic heart disease (RHD) remain major causes of heart failure, stroke and death among African women and children, despite being preventable and imminently treatable. From 21 to 22 ...

    • Severe hyponatraemia in hospital inpatients 

      S Javed Iqbal, PJ Ojwang (BMJ Publishing Group, 1978-12-09)

    • Sickle cell trait (HbAS) is associated with increased expression of erythrocyte complement regulatory proteins CR1 and CD55 levels in children 

      Walter Otieno, Benson B Estambale, Michael M Odera, Stacey MO Gondi, Joash R Aluoch, José A Stoute (International Journal of TROPICAL DISEASE & Health, 2013)
      Aims: Erythrocyte complement regulatory proteins, complement receptor 1 (CR1) and decay accelerating factor (CD55) protect red blood cells (RBCs) from complement mediated damage by controlling complement activation cascade ...

    • Sigmoid volvulus in pregnancy 

      W.O Kaisha; C Bitta; W Kaisha (Annals of African Surgery., 2019)
      Sigmoid volvulus in pregnancy is a rare condition that poses a myriad of challenges in diagnosis and management of the patient. It demands on the clinician a high index of suspicion, immediate treatment involving resuscitation ...

    • Sigmoid volvulus in pregnancy 

      WO Kaisha, C Bitta, W Kaisha (The Surgical Society of Kenya, 2010)
      Sigmoid volvulus in pregnancy is a rare condition that poses a myriad of challenges in diagnosis and management of the patient. It demands on the clinician a high index of suspicion, immediate treatment involving resuscitation ...